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Wonderstruck

Non specific antibody in pregnancy?

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Wonderstruck

I'm 29 weeks with bub no.2. I just had my GTT and other bloods last week (I have hashimotos so they run thyroid bloods etc).

All was as expected except low iron which I figured would be the case as happened last time and an 'unspecified antibody'.

I recall it perhaps coming up post partum with my first and I think it was likely due to be having 4 units of blood transfused post birth. 

My OB suggested a follow up lot of bloods in 4 weeks and a 3rd trimester ultrasound. 

Anyone experienced this? 

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avocado toast

I had a blood transfusion after my first and ended up with anti e and anti d antibodies. My second pregnancy I was monitored fortnightly with bloods and scans checking that it wasn’t affecting baby. It ended up being fine but I’m pregnant again so hopefully will be fine again this time.

If baby starts getting affected then it can be born with rhesus disease which is quite serious. 

Not sure what unspecified antibodies could be and strange that they were only picked up now (mine were picked up at 5 week bloods). You will probably just be monitored closely now until baby arrives. 

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Tinky Winky Woo

I had anti M antibodies and they refused to explain so I looked into it myself.  Had to be careful of bleeding after birth

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Wonderstruck
38 minutes ago, Tinky Winky Woo said:

I had anti M antibodies and they refused to explain so I looked into it myself.  Had to be careful of bleeding after birth

Interesting. With my first I had a 2.5L PPH...

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Gruffalo's Child
13 hours ago, avocado toast said:

I had a blood transfusion after my first and ended up with anti e and anti d antibodies. My second pregnancy I was monitored fortnightly with bloods and scans checking that it wasn’t affecting baby. It ended up being fine but I’m pregnant again so hopefully will be fine again this time.

If baby starts getting affected then it can be born with rhesus disease which is quite serious. 

Not sure what unspecified antibodies could be and strange that they were only picked up now (mine were picked up at 5 week bloods). You will probably just be monitored closely now until baby arrives. 

This was my experience too,  with anti-c and anti-E antibodies.   DH was also tested to see if he had either antigen and he only had the c-antigen, so I was advised that there was a 50% chance the babies could also have this antigen, which meant that the anti-c antibodies that I had developed after my blood transfusion could react with the baby.     In my second pregnancy I was referred to a specialist in maternal fetal medicine who tested DH to see if he had either antigen.  He only had the c-antigen, so I was advised that there was a 50% chance the babies could also have this antigen, which meant that the anti-c antibodies that I had developed after my blood transfusion could react with the baby.    I was put on a plan to  manage this which involved 4-weekly tests if the titre levels remained below 8,  increasing to fortnightly if they went about 8, and fortnightly ultrasounds if they reached 32 or higher.     I was also advised that my baby would be jaundiced at birth.

For most of my second and third pregnancies I ended up having fortnightly blood tests but both babies were born full-term.  They were mildly jaundiced which didn't require any treatment, just monitoring, and were both very healthy.     

OP and Avocado Toast,  wishing you both uneventful pregnancies resulting in very healthy babies!

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Wonderstruck

I spoke to my OB and he's not too concerned. Most likely from the blood transfusion so will check the levels in 4 weeks to see if it changes. 

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