Jump to content

ICSI - anyone have any experience


  • Please log in to reply
19 replies to this topic

#1 shells0701

Posted 06 April 2012 - 08:31 PM

Hi,

We are in the process of doing all the prelim police checks etc and hoping to start our first IVF  cycle in May. I was just wondering if anyone has done IVF with ICSI and if so what was the success of this vs the 'conventional' IVF?

We attended an info session the other night and apart from the cost diff which in the scheme of things is not that much more (I think $400) I was wondering why more people didn't go with this option...would appreciate any thoughts/advice?

#2 LoveMy3Kids

Posted 06 April 2012 - 08:38 PM

We did an ICSI cycle as we have male fertility issues. The sperm were spun off to remove the dodgy ones and then only good ones were injected into the eggs. This gave us the best chance of conception and we luckily achieved a positive on our first cycle.

I would think that if there are only female fertility issues that ICSI isn't necessary as the sperm will fertilise the eggs once given the opportunity.

Good luck with your cycle!

#3 Guest_Dinah_Harris_*

Posted 06 April 2012 - 09:11 PM

We did our ICSI in 2005 so was a while ago now.  From memory, ICSI was significantly more expensive.  This might have changed since then. We used it for male infertility.
ETA, as for success rates, we were always given 40% success rate.  I'm not sure how this rates against conventional IVF.

Edited by Dinah_Harris, 06 April 2012 - 09:13 PM.


#4 libbylu

Posted 06 April 2012 - 09:18 PM

When I looked into it 18 months ago it was about $1500 more expensive per cycle to do ICSI than conventional IVF.  We were initially going to do ICSI due to male factor issues, but our FS tested DSs sperm for zona binding and it was normal, so we ended up doing a conventional cycle.  
Our FS prefers not to do ICSI unless really necessary because you are taking away the natural selection element of fertilisation.  With ICSI, the embryologist chooses which sperm to inject into the egg based on properties that they can observe.  These are not necessarily the sperm that would normally make it into the egg.  When you do conventional IVF the sperm and eggs are all in the dish, so via natural selection, certain sperm beat the others too it.  He said we don't know what the long term affect of using ICSI will be.  However, so far there doesn't seem to be much difference but you are very slightly more likely to get a girl.
Good luck!

#5 Milano

Posted 06 April 2012 - 10:58 PM

QUOTE (LoveMy3Kids @ 06/04/2012, 08:38 PM) <{POST_SNAPBACK}>
I would think that if there are only female fertility issues that ICSI isn't necessary as the sperm will fertilise the eggs once given the opportunity.


Not true unfortunately. My DH has perfect swimmers and we are doing ISCI because I have Low Ovarian Reserve (ie. I'm a poor responder and don't get many eggs). Because of this, ICSI is recommended by our FS to help our minimal eggs get the best chance of fertilising.

#6 LoveMy3Kids

Posted 07 April 2012 - 12:07 AM

QUOTE (Milano @ 06/04/2012, 11:58 PM) <{POST_SNAPBACK}>
Not true unfortunately. My DH has perfect swimmers and we are doing ISCI because I have Low Ovarian Reserve (ie. I'm a poor responder and don't get many eggs). Because of this, ICSI is recommended by our FS to help our minimal eggs get the best chance of fertilising.


I wasn't aware of this. Thanks for clarifying  original.gif . I guess we only had explained to us the information we needed to know.

#7 EloiseIVF

Posted 07 April 2012 - 07:55 AM

Hi Shells,

I also have LOR, like Milano. I've just finished a long down reg cycle. We got 4 good quality eggs and DH's sperm also looked good in the dish, however none would penetrate the eggs so we got no fertilisations. I was told they will do ICSI next time, so I'm stimming back to back. I'm a bit angry that they didn't do it this time when they saw the sperm binding issue, especially since four good eggs for me was in itself a minor miracle. So, in short, we didn't actually have either egg quality or sperm quality issues; just some 'unexplained' non binding sperm. I would say ASK, ASK, ASK all you need to.

Ellie x

#8 emski72

Posted 07 April 2012 - 08:07 AM

We just did ICSI last cycle and $1k extra with City Fertility Clinic.

#9 Monket

Posted 07 April 2012 - 08:19 AM

We did ICSI in 2006 due to sperm binding issues.  FTR, we had a boy!

#10 causeway

Posted 07 April 2012 - 08:29 AM

We did ICSI with both our cycles & the outcome of our second cycle is wearing a green wondersuit, lying next to me. We were with QFG & once medicare rebate came back we were out of pocket by $40. BTW, we did have a girl... I didnt know that ICSI produced more girls! ICSI was recommended due to my LOR & poor numbers, as well as moderate DNA issues in sperm.

#11 Moo point

Posted 07 April 2012 - 08:32 AM

We needed ICSI due to male factor infertility. It was about $1500 more expensive on the initial outlay but we got a good portion back from Medicare (about $2.5k out of pocket per cycle).

From my understanding, it is more successful than conventional IVF for male factor, as the scientists are able to select the best looking (ie normal shape, normal movement) and inject one sperm into each egg. The downside to it is that it relies on them deciding out of a range of thousands or millions of sperm which few look the best. As PPs said, it is also good for issues such as low egg reserve or sperm binding or penetration issues.

We did two full stim cycles with ICSI, with an early loss on the second cycle, and were successful on our third cycle when we combined it with high digital magnification. This allowed the scientists to select only those sperm with no or small vacuoles (air bubbles in the head of the sperm) which cannot be seen on ordinary ICSI magnification and can indicate abnormality in the sperm/chromosomes. I am expecting a boy in 10 weeks original.gif

I have 3 sets of friends who conceived through conventional IVF for endometriosis/unexplained issues with no sperm issues, and another set who conceived through ICSI due to male factor. It is all dependent on your individual issues, and the first IVF cycle you do, whatever the recommendation, can be a learning curve for your specialists as they see how you respond to the treatment and how the sperm/eggs and embryos turn out. Best of luck, OP original.gif

#12 TinMan

Posted 07 April 2012 - 08:38 AM

We did ICSI because of MFI <failed VR>.

We had success on the fourth full cycle.

Good luck, it can be information overload at first.

#13 Brodes

Posted 07 April 2012 - 08:39 AM

My beautiful almost 4yr old daughter is a ICSI frozen blastocyst original.gif We had ICSI done because my husband had, had a vasectomy and his swimmers no longer swam wink.gif

Good luck with your IVF journey!

#14 librablonde

Posted 07 April 2012 - 11:41 AM

I've done ICSI since I started IVF, and am using frozen anon donor sperm.

#15 domestically~challenged

Posted 07 April 2012 - 12:10 PM

We had female factor and male factor and used ICSI.

We used ICSI as my DH's results weren't high enough to do IVF alone.

As mentioned above IVF is the preference as it allows for natural selection.

We had good fert rates with ICSI 11/11 feritlising and then 14/15. Unfortunately we still had to transfer 13 embryos to have success and I do wonder if it would of been sooner had we used straight IVF - quality over quantity and all that.

Best of luck with everything.

#16 specialone

Posted 07 April 2012 - 02:58 PM

Hi,

It only costs $300 for us to do ICSI through our fertility clinic (so not a lot of difference in cost).

We have male fertility problems (only small % mobile sperm).

My first IVF cycle we did a 50/50 split (something you could do?) - which is 50% ICSI and 50% standard IVF. We had 12 eggs to start with. With ICSI we got 4/6 eggs fertilised. With standard IVF we got 6/6 eggs fertlised.

For our second IVF cycle we decided not do do any ICSI as we had got such good fertilisation with standard IVF during our first cycle. Again had 12 eggs to start with. We got 4/12 eggs fertilised - a bit of a disaster... very disappointing. And none of the embryos were any good (none to freeze etc).

We are about to do third IVF cycle and specialist has recommended 100% ICSI which we are contemplating. We will definitely at least do 50/50 as had such low fertility rate for second cycle (only 33%).

Specialist said that on average you get about 60-70% fertilisation from ISCI. Which is better then the 33% we got last cycle without ICSI! We got 66% fertilisation from ISI during the first cycle we did.

I feel ICSI is a bit of a safety net.... makes me feel that we will at least get some embryos... We had such a bad cycle without ICSI in our second cycle that we aren't making that mistake again.

Good luck




#17 shells0701

Posted 07 April 2012 - 09:39 PM

Thank you so much all for your advice and sharing your experiences. The whole process has been very overwhelming to say the least and I fear it's going to get more so!
Our fs suggested Icsi because my husband has sperm antibodies so it's a preferred method.
Thanks again for the info - have learnt quite a bit

#18 jm3

Posted 07 April 2012 - 09:57 PM

QUOTE (libbylu @ 06/04/2012, 08:48 PM) <{POST_SNAPBACK}>
Our FS prefers not to do ICSI unless really necessary because you are taking away the natural selection element of fertilisation.


I didn't think of this at all when the FS suggested that ICSI had a better success rate.  My husband on the other hand said no way no how.  He said IVF is 'artifical' enough without having someone in a lab coat pick the best of each to go together.  Each to their own.

#19 specialone

Posted 08 April 2012 - 02:37 PM

Hi,

Well, I don't think there is much natural about IVF anyway... and if ICSI increases chances of pregnancy then I will go that way. Paying way to much money to lose out due to lack of fertilisation of eggs (like I had last time without ICSI).

Not much natural about making your body produce tonnes of eggs etc. My DH lets me makes most of the choices with IVF (he's happy to do whatever) as he knows its me that ends up going through most of the agony (after EPU I swell up like a balloon etc).

Even if you do natural IVF they still select the best sperm to put with the eggs (and hope that does the trick)... so its not exactly fully natural selection even that way. They weed out the bad looking sperm.

It would have been nice to not do ICSI but I will do whatever it takes to give us the best chance at pregnancy. I think (but will have to check) that my current 2 year old daughter was via ICSI.

All the best - I would go with what your specialist recommends - they know lots of stuff!

#20 NotBitzerMaloney

Posted 08 April 2012 - 03:00 PM

Our first cycle was straight IVF. I wasn't keen on ICSI .... Which changed rapidly when we only had a 20% fertilisation rate from round one (2/10)

Round two we did ICSI and had an 80% fertilization rate.

We ended up having two 5-days blasts from both stim cycles (1 fresh tfr and 1 to freeze), but I was still happy we went with ICSI for round 2 - especially as I got pregnant from that ICSI cycle.



1 user(s) are reading this topic

0 members, 1 guests, 0 anonymous users

 

Share the little things that make you smile

We're giving away a Mountain Buggy nano, the ultimate travel stroller - and here are some of the great entries so far.

Toddler pleads for return of "stolen" nose

A two-year-old's reaction to a game of "got your nose" shows it doesn't take much to make a toddler cry.

The 15 photos new parents share (and five they don't)

From the first scan photo to the baby covered in cake at their first birthday party, there are 15 photos most parents seem to share - and some they don't.

Doctor sings first Happy Birthday to newborns

His job is to deliver babies, but this US obstetrician also has a unique way of celebrating the miracle of life.

Breastfeeding friendly café goes viral

A photo of a breastfeeding-friendly sign in a cafe has been posted to Facebook and shared by hundreds of mums around the world.

First look at the Bugaboo Bee3

The newest Bugaboo Bee ? the Bee3 ? offers a variety of improved features, including a much asked-for bassinet and a rainbow of colour combinations.

Childcare costs, not paid leave, the real issue for parents

Given the choice between maintaining their wage for six months to have a child, or having a reduced rate of pay for a time but a better deal on childcare when returning to work, there are no odds on what most working parents would choose.

Win a Mountain Buggy nano

We?re giving away the new Mountain Buggy Nano - the lightweight travel buggy! So show us the little things that make you smile for your chance to win.

We lost three babies in two years

Our first pregnancy ended the way we all expected it to - with a healthy, happy baby in our arms. What a true blessing he was, for we were not to know the heartache we were about endure.

Family turned back from doomed flight MH17

'There must have been someone watching over us and saying, 'You must not get on that flight,' says mother who narrowly avoided boarding the Malaysian Airlines flight which exploded in mid-air over the Ukraine last night.

The myths and facts about "normal" breastfeeding

When it comes to successful breastfeeding, there is a wide variety to what is "normal", according to new research.

Adorable Skeanie loafers for kids

Your little toddler or preschooler can now get their nautical on with a new range of classic loafers by Australian show brand Skeanie.

My baby is hypermobile

For months, I have been telling myself not to worry that Jasmin isn't crawling or walking. This week I heard the term hypermobile for the first time.

When you don?t bond with your baby

They say that there is no bond greater than the bond between a mother and her child. But for some women, the mother-baby bond takes more time and effort to develop.

Yumi Stynes: Having a baby after a 10-year break

After a long break, Yumi Stynes gets a reminder of the pain - and the pleasure - of giving birth.

Grieving father asks for help to Photoshop his daughter's image

When Nathan Steffel's daughter Sophia died from a liver condition at just 6 weeks old, he reached out for someone to create a beautiful image of his little girl.

Raising kids in a 'low media' home

Can you imagine a life without TV or computers? Some parents are opting for a low-tech, screen-free life for their kids.

Download now: Essential Kids Activity Finder app

Got bored kids? Quickly find the best activities for kids wherever you are in Australia with the Essential Kids app.

 
Advertisement
 
Advertisement
 
 
 

What's hot on EB

Win a Mountain Buggy nano

We?re giving away the new Mountain Buggy Nano - the lightweight travel buggy! So show us the little things that make you smile for your chance to win.

Be careful what you say, your baby is listening

The importance of speaking to your baby even if they are not old enough to answer back has been highlighted by new research.

WIN two Sea-Bands plus $1000

Three lucky fans can win a Sea-Band Prize Pack valued at over $1000 each, which includes two Sea-Bands plus a $1000 Eftpos Gift Card!

The beautiful moment a baby was born at the side of a road

It's not where she expected to give birth, but mum Corrine Cinatl is delighted that her daughter's roadside arrival was captured in a series of beautiful photos.

Doctor sings first Happy Birthday to newborns

His job is to deliver babies, but this US obstetrician also has a unique way of celebrating the miracle of life.

The Nappy Collective starts new drive

It's that time of year when the dedicated volunteers at The Nappy Collective do their bit to help out mums and children in need - and they need your help.

Baby shower cake wrecks

From misshapen cake babies to questionable text, from odd colour choices to internal organ recreation, these are the baby shower cakes that taste forgot.

Photographer captures the beauty of adoption

The love of a family is usually tough to capture on camera. This is an exception.

Pregnancy progression photo ideas

Want to record your pregnancy as your belly grows? Here are some creative, fun ideas for photo shoots along the way.

The myths and facts about "normal" breastfeeding

When it comes to successful breastfeeding, there is a wide variety to what is "normal", according to new research.

Tin can craft and DIY ideas

Got a few old formula, Milo or coffee cans around the house? Use these fantastic upcycling ideas to create items for around the house and yard.

Dads meet their newborn for the first time

Emotional photos of two fathers meeting their newborn son have resonated with viewers worldwide, attracting thousands of Facebook likes and shares.

Skin safety isn't just a summer worry

Lax about the slip slop slap with your kids as weather turns cooler? Here's a reminder as to why we have to remain vigilant for our children?s future health.

Personalised baby gifts

We've scoured the internet to find gorgeous personalised keepsakes and nursery decor to record baby name and dates. They make great gifts for christenings, name days and birthdays! (All prices in AU.)

Creative sleeping baby photoshoots

See how some parents and photographers have captured sleeping babies in unusual positions and using different props.

DIY kitchen and food hacks

DIY your way to a better kitchen and make cooking easier with our clever hacks. (Some content reproduced with permission from mashable.com.)

Winter warmers for babies and toddlers

Your baby or toddler will be nice and snug in these beautiful and fun winter pieces. Most are hand-made or knitted, and they're all designed to keep your little one toastie - and adorable!

 

Mind, body, beauty, life

Making time for me

We look at your wellbeing, covering health, relationships, beauty and fashion, mind and body.

 
Advertisement
 
 
Essential Baby and Essential Kids is the place to find parenting information and parenting support relating to conception, pregnancy, birth, babies, toddlers, kids, maternity, family budgeting, family travel, nutrition and wellbeing, family entertainment, kids entertainment, tips for the family home, child-friendly recipes and parenting. Try our pregnancy due date calculator to determine your due date, or our ovulation calculator to predict ovulation and your fertile period. Our pregnancy week by week guide shows your baby's stages of development. Access our very active mum's discussion groups in the Essential Baby forums or the Essential Kids forums to talk to mums about conception, pregnancy, birth, babies, toddlers, kids and parenting lifestyle. Essential Baby also offers a baby names database of more than 22,000 baby names, popular baby names, boys' names, girls' names and baby names advice in our baby names forum. Essential Kids features a range of free printable worksheets for kids from preschool years through to primary school years. For the latest baby clothes, maternity clothes, maternity accessories, toddler products, kids toys and kids clothing, breastfeeding and other parenting resources, check out Essential Baby and Essential Kids.