Jump to content

ICSI - anyone have any experience


  • Please log in to reply
19 replies to this topic

#1 shells0701

Posted 06 April 2012 - 08:31 PM

Hi,

We are in the process of doing all the prelim police checks etc and hoping to start our first IVF  cycle in May. I was just wondering if anyone has done IVF with ICSI and if so what was the success of this vs the 'conventional' IVF?

We attended an info session the other night and apart from the cost diff which in the scheme of things is not that much more (I think $400) I was wondering why more people didn't go with this option...would appreciate any thoughts/advice?

#2 LoveMy3Kids

Posted 06 April 2012 - 08:38 PM

We did an ICSI cycle as we have male fertility issues. The sperm were spun off to remove the dodgy ones and then only good ones were injected into the eggs. This gave us the best chance of conception and we luckily achieved a positive on our first cycle.

I would think that if there are only female fertility issues that ICSI isn't necessary as the sperm will fertilise the eggs once given the opportunity.

Good luck with your cycle!

#3 Guest_Dinah_Harris_*

Posted 06 April 2012 - 09:11 PM

We did our ICSI in 2005 so was a while ago now.  From memory, ICSI was significantly more expensive.  This might have changed since then. We used it for male infertility.
ETA, as for success rates, we were always given 40% success rate.  I'm not sure how this rates against conventional IVF.

Edited by Dinah_Harris, 06 April 2012 - 09:13 PM.


#4 libbylu

Posted 06 April 2012 - 09:18 PM

When I looked into it 18 months ago it was about $1500 more expensive per cycle to do ICSI than conventional IVF.  We were initially going to do ICSI due to male factor issues, but our FS tested DSs sperm for zona binding and it was normal, so we ended up doing a conventional cycle.  
Our FS prefers not to do ICSI unless really necessary because you are taking away the natural selection element of fertilisation.  With ICSI, the embryologist chooses which sperm to inject into the egg based on properties that they can observe.  These are not necessarily the sperm that would normally make it into the egg.  When you do conventional IVF the sperm and eggs are all in the dish, so via natural selection, certain sperm beat the others too it.  He said we don't know what the long term affect of using ICSI will be.  However, so far there doesn't seem to be much difference but you are very slightly more likely to get a girl.
Good luck!

#5 Milano

Posted 06 April 2012 - 10:58 PM

QUOTE (LoveMy3Kids @ 06/04/2012, 08:38 PM) <{POST_SNAPBACK}>
I would think that if there are only female fertility issues that ICSI isn't necessary as the sperm will fertilise the eggs once given the opportunity.


Not true unfortunately. My DH has perfect swimmers and we are doing ISCI because I have Low Ovarian Reserve (ie. I'm a poor responder and don't get many eggs). Because of this, ICSI is recommended by our FS to help our minimal eggs get the best chance of fertilising.

#6 LoveMy3Kids

Posted 07 April 2012 - 12:07 AM

QUOTE (Milano @ 06/04/2012, 11:58 PM) <{POST_SNAPBACK}>
Not true unfortunately. My DH has perfect swimmers and we are doing ISCI because I have Low Ovarian Reserve (ie. I'm a poor responder and don't get many eggs). Because of this, ICSI is recommended by our FS to help our minimal eggs get the best chance of fertilising.


I wasn't aware of this. Thanks for clarifying  original.gif . I guess we only had explained to us the information we needed to know.

#7 EloiseIVF

Posted 07 April 2012 - 07:55 AM

Hi Shells,

I also have LOR, like Milano. I've just finished a long down reg cycle. We got 4 good quality eggs and DH's sperm also looked good in the dish, however none would penetrate the eggs so we got no fertilisations. I was told they will do ICSI next time, so I'm stimming back to back. I'm a bit angry that they didn't do it this time when they saw the sperm binding issue, especially since four good eggs for me was in itself a minor miracle. So, in short, we didn't actually have either egg quality or sperm quality issues; just some 'unexplained' non binding sperm. I would say ASK, ASK, ASK all you need to.

Ellie x

#8 emski72

Posted 07 April 2012 - 08:07 AM

We just did ICSI last cycle and $1k extra with City Fertility Clinic.

#9 Monket

Posted 07 April 2012 - 08:19 AM

We did ICSI in 2006 due to sperm binding issues.  FTR, we had a boy!

#10 causeway

Posted 07 April 2012 - 08:29 AM

We did ICSI with both our cycles & the outcome of our second cycle is wearing a green wondersuit, lying next to me. We were with QFG & once medicare rebate came back we were out of pocket by $40. BTW, we did have a girl... I didnt know that ICSI produced more girls! ICSI was recommended due to my LOR & poor numbers, as well as moderate DNA issues in sperm.

#11 Moo point

Posted 07 April 2012 - 08:32 AM

We needed ICSI due to male factor infertility. It was about $1500 more expensive on the initial outlay but we got a good portion back from Medicare (about $2.5k out of pocket per cycle).

From my understanding, it is more successful than conventional IVF for male factor, as the scientists are able to select the best looking (ie normal shape, normal movement) and inject one sperm into each egg. The downside to it is that it relies on them deciding out of a range of thousands or millions of sperm which few look the best. As PPs said, it is also good for issues such as low egg reserve or sperm binding or penetration issues.

We did two full stim cycles with ICSI, with an early loss on the second cycle, and were successful on our third cycle when we combined it with high digital magnification. This allowed the scientists to select only those sperm with no or small vacuoles (air bubbles in the head of the sperm) which cannot be seen on ordinary ICSI magnification and can indicate abnormality in the sperm/chromosomes. I am expecting a boy in 10 weeks original.gif

I have 3 sets of friends who conceived through conventional IVF for endometriosis/unexplained issues with no sperm issues, and another set who conceived through ICSI due to male factor. It is all dependent on your individual issues, and the first IVF cycle you do, whatever the recommendation, can be a learning curve for your specialists as they see how you respond to the treatment and how the sperm/eggs and embryos turn out. Best of luck, OP original.gif

#12 TinMan

Posted 07 April 2012 - 08:38 AM

We did ICSI because of MFI <failed VR>.

We had success on the fourth full cycle.

Good luck, it can be information overload at first.

#13 Brodes

Posted 07 April 2012 - 08:39 AM

My beautiful almost 4yr old daughter is a ICSI frozen blastocyst original.gif We had ICSI done because my husband had, had a vasectomy and his swimmers no longer swam wink.gif

Good luck with your IVF journey!

#14 librablonde

Posted 07 April 2012 - 11:41 AM

I've done ICSI since I started IVF, and am using frozen anon donor sperm.

#15 domestically~challenged

Posted 07 April 2012 - 12:10 PM

We had female factor and male factor and used ICSI.

We used ICSI as my DH's results weren't high enough to do IVF alone.

As mentioned above IVF is the preference as it allows for natural selection.

We had good fert rates with ICSI 11/11 feritlising and then 14/15. Unfortunately we still had to transfer 13 embryos to have success and I do wonder if it would of been sooner had we used straight IVF - quality over quantity and all that.

Best of luck with everything.

#16 specialone

Posted 07 April 2012 - 02:58 PM

Hi,

It only costs $300 for us to do ICSI through our fertility clinic (so not a lot of difference in cost).

We have male fertility problems (only small % mobile sperm).

My first IVF cycle we did a 50/50 split (something you could do?) - which is 50% ICSI and 50% standard IVF. We had 12 eggs to start with. With ICSI we got 4/6 eggs fertilised. With standard IVF we got 6/6 eggs fertlised.

For our second IVF cycle we decided not do do any ICSI as we had got such good fertilisation with standard IVF during our first cycle. Again had 12 eggs to start with. We got 4/12 eggs fertilised - a bit of a disaster... very disappointing. And none of the embryos were any good (none to freeze etc).

We are about to do third IVF cycle and specialist has recommended 100% ICSI which we are contemplating. We will definitely at least do 50/50 as had such low fertility rate for second cycle (only 33%).

Specialist said that on average you get about 60-70% fertilisation from ISCI. Which is better then the 33% we got last cycle without ICSI! We got 66% fertilisation from ISI during the first cycle we did.

I feel ICSI is a bit of a safety net.... makes me feel that we will at least get some embryos... We had such a bad cycle without ICSI in our second cycle that we aren't making that mistake again.

Good luck




#17 shells0701

Posted 07 April 2012 - 09:39 PM

Thank you so much all for your advice and sharing your experiences. The whole process has been very overwhelming to say the least and I fear it's going to get more so!
Our fs suggested Icsi because my husband has sperm antibodies so it's a preferred method.
Thanks again for the info - have learnt quite a bit

#18 jm3

Posted 07 April 2012 - 09:57 PM

QUOTE (libbylu @ 06/04/2012, 08:48 PM) <{POST_SNAPBACK}>
Our FS prefers not to do ICSI unless really necessary because you are taking away the natural selection element of fertilisation.


I didn't think of this at all when the FS suggested that ICSI had a better success rate.  My husband on the other hand said no way no how.  He said IVF is 'artifical' enough without having someone in a lab coat pick the best of each to go together.  Each to their own.

#19 specialone

Posted 08 April 2012 - 02:37 PM

Hi,

Well, I don't think there is much natural about IVF anyway... and if ICSI increases chances of pregnancy then I will go that way. Paying way to much money to lose out due to lack of fertilisation of eggs (like I had last time without ICSI).

Not much natural about making your body produce tonnes of eggs etc. My DH lets me makes most of the choices with IVF (he's happy to do whatever) as he knows its me that ends up going through most of the agony (after EPU I swell up like a balloon etc).

Even if you do natural IVF they still select the best sperm to put with the eggs (and hope that does the trick)... so its not exactly fully natural selection even that way. They weed out the bad looking sperm.

It would have been nice to not do ICSI but I will do whatever it takes to give us the best chance at pregnancy. I think (but will have to check) that my current 2 year old daughter was via ICSI.

All the best - I would go with what your specialist recommends - they know lots of stuff!

#20 NotBitzerMaloney

Posted 08 April 2012 - 03:00 PM

Our first cycle was straight IVF. I wasn't keen on ICSI .... Which changed rapidly when we only had a 20% fertilisation rate from round one (2/10)

Round two we did ICSI and had an 80% fertilization rate.

We ended up having two 5-days blasts from both stim cycles (1 fresh tfr and 1 to freeze), but I was still happy we went with ICSI for round 2 - especially as I got pregnant from that ICSI cycle.



1 user(s) are reading this topic

0 members, 1 guests, 0 anonymous users

 

Special Ticket Offer, Save $8!

The Essential Baby & Toddler Show is back this April! Save $8 off the door price for a limited time only!

Why I breastfed my son until he was three

The fact that I not only breastfed my son, but breastfed him for three and a half years, seems pretty incredible in retrospect.

Do babies and young children see ghosts?

Do babies and young children see ghosts? If you’ve pondered the question, you’re not alone.

15 years with Essential Baby: meet Therese

"Life has a funny way of giving you what you need when you need it the most."

Mum causes a stir by taking a stand against leggings

A mum has found herself the subject of debate after claiming tight bottoms cause lustful thoughts in men.

Don't set a parenting goal for 2015 - do this instead

The problem with goal setting as a parent is the measure. How do we really know if we’re succeeding?

5 pregnancy myths that just won't go away

When you're expecting, it often seems like everyone is keen to offer advice about what you should and shouldn't do in the interests of your health and wellbeing.

RPA hospital contacting mums after discovering vaccine storage fault

Sydney's Royal Prince Alfred Hospital (RPA) is trying to contact women who had babies at the facility after discovering a fault in a refrigerator containing vaccines.

'Nutella' not a baby name, French court says

A French court has blocked parents from naming their baby girl after the hazelnut spread Nutella, arguing it would make her the target of mockery.

Why I'm never calling myself 'just a mum' again

I’ve grown three human beings. I feed them, dress them, teach them, care for them and love them 24 hours a day. Yet for eight years, when I meet new people and they’ve asked me what I do, I tell them: “I’m just a mum”.

Rosie Batty named 2015 Australian of the Year

One year ago, Rosie Batty could not have imagined she'd be where she is. Tonight the grieving mum who put domestic violence on the national agenda was named Australian of the Year.

Five reasons to hug more

Hugging – some of us thrive on it, even depend on it – and then there are those who don't care for it really. So, are they missing out?

Help - my three-year-old has started throwing tantrums

My daughter never went through the "terrible twos" but began throwing wild tantrums shortly after her third birthday.

That's commitment

First peek at Sonia Kruger's daughter Maggie

"She smells so good, I could eat her," Kruger tells co-host David Campbell.

Mum assists in own caesarean surgery

A mum who partly delivered her own twins during a caesarean has encouraged other women to take control of their birthing experience.

How to handle common childhood regressions

Regression can be a natural and common part of development prompted by a variety of factors, but that doesn't make it less frustrating.

Disgruntled dad's pram ad goes viral

When buying a second hand pram, there are lots of things to take into consideration. 

Man discovers he's a dad after finding 55-year-old letter

Discovering you are about to father a baby is startling enough - never mind finding out you have a 61-year-old son.

15 thoughts mums have during a tantrum

Ranging from mild to feral and triggered by events both minor and major, tantrums certainly keep life interesting.

Natural pain relief in the early stages of labour

While managing labour pains on your own can be daunting, there are a number of natural pain relief options to help you cope until you are admitted to hospital.

Win an Octonauts prize pack

To celebrate the launch of Octonauts Live! Operation Reef Shield, a spectacular underwater adventure live on stage, we are giving away an amazing Octonauts prize pack to one lucky fan.

Download now: Essential Kids Activity Finder app

Got bored kids? Quickly find the best activities for kids wherever you are in Australia with the Essential Kids app.

 
Advertisement
 
Advertisement
 
 
 

What's hot on EB

Forgotten Baby Syndrome claims the life of toddler

One baby dies every eight days in the back of a car in the US, victims of 'forgotten baby syndrome'.

For a brief time, I was touched by an angel

For a brief time, I was touched by an angel. You stole my heart, and changed me into the women I am today.

Chinese woman gives birth to quintuplets

After six years of trying for a baby, a couple’s dreams have come true many times over after the mum gave birth to quintuplets this week.

Chrissie Swan has reached her "sex quota"

Chrissie Swan says she and her partner have sex once a year due to her fear of falling pregnant.

Stars help save choking babies

It's an important lesson to learn, but one that busy new mums and dads might overlook until it's too late.

New Girl star Zooey Deschanel pregnant

Actress Zooey Deschanel is expecting her first child with her producer boyfriend Jacob Pechenik.

16 times 'dad reflexes' saved the day

Of course, in some cases they may be the ones who actually got their child into a precarious position in the first place, but we'll ignore that for now.

Couple's 'non-traditional' pregnancy announcement goes viral

Knowing you are not the father of your pregnant wife's baby would usually indicate a rocky relationship ahead for traditional parents.

The trials and tribulations of identical triplet newborns

Pip Donnelly is still playing spot the difference with her newborn identical triplets, Isabelle, Georgina and Frankie.

Win an Octonauts prize pack

To celebrate the launch of Octonauts Live! Operation Reef Shield, a spectacular underwater adventure live on stage, we are giving away an amazing Octonauts prize pack to one lucky fan.

Earthquake baby thriving five years on

Jenny Alexis is lucky to be alive after spending four days buried in the rubble of the 2010 Haitian earthquake, but now she's a thriving five year old.

Please don't say I'm lucky because I was adopted

On the one hand I was having a regular life with friends and sports and sleepovers and school. But I was also always wondering: Did my mother love me? What was wrong with me?

An open letter to non-parents who offer advice on child-rearing

Kitty, when you’re the parent of my child you’re welcome to wade in with an opinion – but until then, I’d prefer you to have a supportive ear and a glass of wine ready.

Couple arrested over baby gun video

A US couple faces charges after investigators say they found mobile phone videos showing the woman's 12-month-old daughter putting a handgun in her mouth.

NSW Health dumps 10-year limit on frozen embryos

A 10-year time limit on storing frozen embryos that were created with donor sperm has been dropped by the NSW government.

How my happy-go-lucky husband became a monster

Sharan Nicholson-Rogers watched her husband change from a happy-go-lucky police officer into an unpredictable man prone to violent and emotional outbursts.

Dads-to-be experience hormonal changes, too

Dads-to-be experience hormonal changes in line with their pregnant partners, a new study shows.

'They were just doing their job': mum of toddler killed in police chase gone wrong

"They were just doing their job. I feel so sorry for them. It is all just too sad."

Miscarriages to be formally recognised by NSW government

Women who miscarry will be able to obtain an optional "recognition of loss" certificate as a formal recognition of their often heartbreaking loss.

Cafe cubby house 'too noisy' for neighbours

Teenage parties, domestic disputes, or raucous late night pubs are the things that usually come to mind when you think neighbourhood noise complaints.

Dad films baby playing with snake

Most parents would not consider a snake an appropriate playmate for their baby, but a US dad who filmed his daughter playing with a python has defended himself against criticism.

Clever breastfeeding products

Check out this range of products designed to help make your breastfeeding journey more enjoyable, manageable and convenient.

 

Back to School Offer

Findababysitter.com.au

We've got you covered for this school year. Use www.findababysitter.com.au to meet local nannies now.

 
Advertisement
 
 
Essential Baby and Essential Kids is the place to find parenting information and parenting support relating to conception, pregnancy, birth, babies, toddlers, kids, maternity, family budgeting, family travel, nutrition and wellbeing, family entertainment, kids entertainment, tips for the family home, child-friendly recipes and parenting. Try our pregnancy due date calculator to determine your due date, or our ovulation calculator to predict ovulation and your fertile period. Our pregnancy week by week guide shows your baby's stages of development. Access our very active mum's discussion groups in the Essential Baby forums or the Essential Kids forums to talk to mums about conception, pregnancy, birth, babies, toddlers, kids and parenting lifestyle. Essential Baby also offers a baby names database of more than 22,000 baby names, popular baby names, boys' names, girls' names and baby names advice in our baby names forum. Essential Kids features a range of free printable worksheets for kids from preschool years through to primary school years. For the latest baby clothes, maternity clothes, maternity accessories, toddler products, kids toys and kids clothing, breastfeeding and other parenting resources, check out Essential Baby and Essential Kids.