Jump to content

ICSI - anyone have any experience

  • Please log in to reply
19 replies to this topic

#1 shells0701

Posted 06 April 2012 - 08:31 PM


We are in the process of doing all the prelim police checks etc and hoping to start our first IVF  cycle in May. I was just wondering if anyone has done IVF with ICSI and if so what was the success of this vs the 'conventional' IVF?

We attended an info session the other night and apart from the cost diff which in the scheme of things is not that much more (I think $400) I was wondering why more people didn't go with this option...would appreciate any thoughts/advice?

#2 LoveMy3Kids

Posted 06 April 2012 - 08:38 PM

We did an ICSI cycle as we have male fertility issues. The sperm were spun off to remove the dodgy ones and then only good ones were injected into the eggs. This gave us the best chance of conception and we luckily achieved a positive on our first cycle.

I would think that if there are only female fertility issues that ICSI isn't necessary as the sperm will fertilise the eggs once given the opportunity.

Good luck with your cycle!

#3 Guest_Dinah_Harris_*

Posted 06 April 2012 - 09:11 PM

We did our ICSI in 2005 so was a while ago now.  From memory, ICSI was significantly more expensive.  This might have changed since then. We used it for male infertility.
ETA, as for success rates, we were always given 40% success rate.  I'm not sure how this rates against conventional IVF.

Edited by Dinah_Harris, 06 April 2012 - 09:13 PM.

#4 libbylu

Posted 06 April 2012 - 09:18 PM

When I looked into it 18 months ago it was about $1500 more expensive per cycle to do ICSI than conventional IVF.  We were initially going to do ICSI due to male factor issues, but our FS tested DSs sperm for zona binding and it was normal, so we ended up doing a conventional cycle.  
Our FS prefers not to do ICSI unless really necessary because you are taking away the natural selection element of fertilisation.  With ICSI, the embryologist chooses which sperm to inject into the egg based on properties that they can observe.  These are not necessarily the sperm that would normally make it into the egg.  When you do conventional IVF the sperm and eggs are all in the dish, so via natural selection, certain sperm beat the others too it.  He said we don't know what the long term affect of using ICSI will be.  However, so far there doesn't seem to be much difference but you are very slightly more likely to get a girl.
Good luck!

#5 Milano

Posted 06 April 2012 - 10:58 PM

QUOTE (LoveMy3Kids @ 06/04/2012, 08:38 PM) <{POST_SNAPBACK}>
I would think that if there are only female fertility issues that ICSI isn't necessary as the sperm will fertilise the eggs once given the opportunity.

Not true unfortunately. My DH has perfect swimmers and we are doing ISCI because I have Low Ovarian Reserve (ie. I'm a poor responder and don't get many eggs). Because of this, ICSI is recommended by our FS to help our minimal eggs get the best chance of fertilising.

#6 LoveMy3Kids

Posted 07 April 2012 - 12:07 AM

QUOTE (Milano @ 06/04/2012, 11:58 PM) <{POST_SNAPBACK}>
Not true unfortunately. My DH has perfect swimmers and we are doing ISCI because I have Low Ovarian Reserve (ie. I'm a poor responder and don't get many eggs). Because of this, ICSI is recommended by our FS to help our minimal eggs get the best chance of fertilising.

I wasn't aware of this. Thanks for clarifying  original.gif . I guess we only had explained to us the information we needed to know.

#7 EloiseIVF

Posted 07 April 2012 - 07:55 AM

Hi Shells,

I also have LOR, like Milano. I've just finished a long down reg cycle. We got 4 good quality eggs and DH's sperm also looked good in the dish, however none would penetrate the eggs so we got no fertilisations. I was told they will do ICSI next time, so I'm stimming back to back. I'm a bit angry that they didn't do it this time when they saw the sperm binding issue, especially since four good eggs for me was in itself a minor miracle. So, in short, we didn't actually have either egg quality or sperm quality issues; just some 'unexplained' non binding sperm. I would say ASK, ASK, ASK all you need to.

Ellie x

#8 emski72

Posted 07 April 2012 - 08:07 AM

We just did ICSI last cycle and $1k extra with City Fertility Clinic.

#9 Monket

Posted 07 April 2012 - 08:19 AM

We did ICSI in 2006 due to sperm binding issues.  FTR, we had a boy!

#10 causeway

Posted 07 April 2012 - 08:29 AM

We did ICSI with both our cycles & the outcome of our second cycle is wearing a green wondersuit, lying next to me. We were with QFG & once medicare rebate came back we were out of pocket by $40. BTW, we did have a girl... I didnt know that ICSI produced more girls! ICSI was recommended due to my LOR & poor numbers, as well as moderate DNA issues in sperm.

#11 Moo point

Posted 07 April 2012 - 08:32 AM

We needed ICSI due to male factor infertility. It was about $1500 more expensive on the initial outlay but we got a good portion back from Medicare (about $2.5k out of pocket per cycle).

From my understanding, it is more successful than conventional IVF for male factor, as the scientists are able to select the best looking (ie normal shape, normal movement) and inject one sperm into each egg. The downside to it is that it relies on them deciding out of a range of thousands or millions of sperm which few look the best. As PPs said, it is also good for issues such as low egg reserve or sperm binding or penetration issues.

We did two full stim cycles with ICSI, with an early loss on the second cycle, and were successful on our third cycle when we combined it with high digital magnification. This allowed the scientists to select only those sperm with no or small vacuoles (air bubbles in the head of the sperm) which cannot be seen on ordinary ICSI magnification and can indicate abnormality in the sperm/chromosomes. I am expecting a boy in 10 weeks original.gif

I have 3 sets of friends who conceived through conventional IVF for endometriosis/unexplained issues with no sperm issues, and another set who conceived through ICSI due to male factor. It is all dependent on your individual issues, and the first IVF cycle you do, whatever the recommendation, can be a learning curve for your specialists as they see how you respond to the treatment and how the sperm/eggs and embryos turn out. Best of luck, OP original.gif

#12 TinMan

Posted 07 April 2012 - 08:38 AM

We did ICSI because of MFI <failed VR>.

We had success on the fourth full cycle.

Good luck, it can be information overload at first.

#13 Brodes

Posted 07 April 2012 - 08:39 AM

My beautiful almost 4yr old daughter is a ICSI frozen blastocyst original.gif We had ICSI done because my husband had, had a vasectomy and his swimmers no longer swam wink.gif

Good luck with your IVF journey!

#14 librablonde

Posted 07 April 2012 - 11:41 AM

I've done ICSI since I started IVF, and am using frozen anon donor sperm.

#15 domestically~challenged

Posted 07 April 2012 - 12:10 PM

We had female factor and male factor and used ICSI.

We used ICSI as my DH's results weren't high enough to do IVF alone.

As mentioned above IVF is the preference as it allows for natural selection.

We had good fert rates with ICSI 11/11 feritlising and then 14/15. Unfortunately we still had to transfer 13 embryos to have success and I do wonder if it would of been sooner had we used straight IVF - quality over quantity and all that.

Best of luck with everything.

#16 specialone

Posted 07 April 2012 - 02:58 PM


It only costs $300 for us to do ICSI through our fertility clinic (so not a lot of difference in cost).

We have male fertility problems (only small % mobile sperm).

My first IVF cycle we did a 50/50 split (something you could do?) - which is 50% ICSI and 50% standard IVF. We had 12 eggs to start with. With ICSI we got 4/6 eggs fertilised. With standard IVF we got 6/6 eggs fertlised.

For our second IVF cycle we decided not do do any ICSI as we had got such good fertilisation with standard IVF during our first cycle. Again had 12 eggs to start with. We got 4/12 eggs fertilised - a bit of a disaster... very disappointing. And none of the embryos were any good (none to freeze etc).

We are about to do third IVF cycle and specialist has recommended 100% ICSI which we are contemplating. We will definitely at least do 50/50 as had such low fertility rate for second cycle (only 33%).

Specialist said that on average you get about 60-70% fertilisation from ISCI. Which is better then the 33% we got last cycle without ICSI! We got 66% fertilisation from ISI during the first cycle we did.

I feel ICSI is a bit of a safety net.... makes me feel that we will at least get some embryos... We had such a bad cycle without ICSI in our second cycle that we aren't making that mistake again.

Good luck

#17 shells0701

Posted 07 April 2012 - 09:39 PM

Thank you so much all for your advice and sharing your experiences. The whole process has been very overwhelming to say the least and I fear it's going to get more so!
Our fs suggested Icsi because my husband has sperm antibodies so it's a preferred method.
Thanks again for the info - have learnt quite a bit

#18 jm3

Posted 07 April 2012 - 09:57 PM

QUOTE (libbylu @ 06/04/2012, 08:48 PM) <{POST_SNAPBACK}>
Our FS prefers not to do ICSI unless really necessary because you are taking away the natural selection element of fertilisation.

I didn't think of this at all when the FS suggested that ICSI had a better success rate.  My husband on the other hand said no way no how.  He said IVF is 'artifical' enough without having someone in a lab coat pick the best of each to go together.  Each to their own.

#19 specialone

Posted 08 April 2012 - 02:37 PM


Well, I don't think there is much natural about IVF anyway... and if ICSI increases chances of pregnancy then I will go that way. Paying way to much money to lose out due to lack of fertilisation of eggs (like I had last time without ICSI).

Not much natural about making your body produce tonnes of eggs etc. My DH lets me makes most of the choices with IVF (he's happy to do whatever) as he knows its me that ends up going through most of the agony (after EPU I swell up like a balloon etc).

Even if you do natural IVF they still select the best sperm to put with the eggs (and hope that does the trick)... so its not exactly fully natural selection even that way. They weed out the bad looking sperm.

It would have been nice to not do ICSI but I will do whatever it takes to give us the best chance at pregnancy. I think (but will have to check) that my current 2 year old daughter was via ICSI.

All the best - I would go with what your specialist recommends - they know lots of stuff!

#20 NotBitzerMaloney

Posted 08 April 2012 - 03:00 PM

Our first cycle was straight IVF. I wasn't keen on ICSI .... Which changed rapidly when we only had a 20% fertilisation rate from round one (2/10)

Round two we did ICSI and had an 80% fertilization rate.

We ended up having two 5-days blasts from both stim cycles (1 fresh tfr and 1 to freeze), but I was still happy we went with ICSI for round 2 - especially as I got pregnant from that ICSI cycle.

2 user(s) are reading this topic

0 members, 2 guests, 0 anonymous users


First look at Renee Zellweger in Bridget Jones's Baby

Bridget is now in her 40s and is a successful publishing executive - but also has a pregnancy to contend with as well.

Newlyweds send bill to no-show guests

Planning a wedding can be stressful – and, as most newlyweds can attest, it can be very costly, too.

Claire Danes: acting out postnatal depression was difficult

Actress Claire Danes found it difficult pretending to have postnatal depression in Homeland, as she had just become a new mother herself.

Sneak peek: Geleeo self-cooling pram & high chair liners

We just spotted Geleeo, a brand new self-cooling pram liner you can buy in time for summer.

The moment a 92-year-old meets her great grandaughter

It's a heart-warming photo this family will treasure forever.

How to prepare for breastfeeding when you're still pregnant

While every woman's breastfeeding journey is different, many hurdles are shared. Knowing what to expect will enable you to make informed decisions if - or when - you meet challenges along the way.

Sneak peek: new Love Mae bamboo dinnerware designs

We do love ourselves some brand new designs in tried and true products. The renowned bamboo dinnerware from Love Mae has just had several more members join the family, in addition to a brand new website.

Mum who killed paedophile gets reduced sentence

A mother-of-five who killed a paedophile has had her jail sentence reduced by a judge who described her case as a "truly exceptional" one.

Toddler's silent debate with mum about naptime

He might not utter a single word - but this toddler is having a great debate with his mother about nap time.

Silence is golden ... or is it?

Silence is golden, or so the saying goes. But when it comes to children, quite the opposite is true.

Awards 2015: Vote now for a chance to win $2000

Vote for your favourite pregnancy, baby and toddler products for your chance to win your share of $2500 in cash prizes.

Scientists identify potential birth control 'pill' for men

Two drugs that help suppress the immune system in organ transplant patients may have a future as the long-sought birth control "pill" for men, new research suggests.

Running for beginners: taking the first steps

It's that time of year when the weather warms up and there's more opportunity to get out and go for a jog.

Tips for turning yourself into a morning person

Mornings are a great time to spend time in reflection or to get outside and get moving.

Thousands sign petition for unborn babies killed by domestic violence

Almost 8000 people have signed a petition calling for a law to recognise unborn babies killed by domestic violence in NSW.

Pregnant Sarah Harris tells body-shamers to 'get stuffed'

Television presenter Sarah Harris has a message for anyone who tries to body-shame pregnant women or new mums.

In defence of 'brexting'

Mums spend literally hours a day with a baby attached to their boob, or giving them a bottle. Surely they don't all need to be spent looking at the baby?

How a fellow passenger made a mum's day on a flight

As any parent who has ever travelled with a baby knows it can be a daunting experience. The stares and attitude of unsympathetic fellow travellers only serve to make the journey even more stressful. 


What's hot on EB

Stella McCartney honours mum with lacy bra

Fashion designer Stella McCartney has honoured her late mum, Linda McCartney, by designing a special bra for post-mastectomy patients.

Don't panic: A granddad midwife's guide for dads-to-be

Mark Harris has helped deliver 500 babies. And he's now telling fathers what to expect.

How to be a calm parent when you're feeling anything but

Being a calm parent takes a lot of work, sometimes more than is obvious to those around us.

The joy and isolation of being a stay-at-home dad

It's cool, kind of like a second childhood. I love him to bits and think, on average, I'm an okay dad. But I also want to talk about the other stuff.

How baby Teddy's short life is helping save thousands of lives

He may have only lived for 100 minutes, but that didn't stop baby Teddy from saving the lives of others.

A heartbreaking trail of missed chances in death of baby forgotten in car

A haunting reminder to stay mindful about babies in cars, especially as we approach summer.

What to do if your baby has tongue-tie

Tongue-tie can cause feeding problems. However once it is diagnosed, the condition can be easily treated.

How to move house without losing your mind

Some people move frequently, while others like to stay put. But everyone finds it stressful.

'She had nowhere to go': how new mum's life began to unravel

The birth of her first child should have been happiest of times for Campsie mother Phuong Cao, but friends say it marked the beginning of when her life began to unravel. 

Women giving birth to a son keep some of his Y chromosomes

It was an experiment doomed to failure - they were looking for male cells in female bodies. And their search was stunningly successful.

Photos: How babies fit in the womb

A gorgeous photo series shows babies in the first hours after their birth - as they were positioned in the womb.

Baby tries to persuade stubborn bulldog to walk, fails

We don't know what he's saying, but this baby has a very clear message for his bulldog pal: let's walk - NOW.

The best toddler gift ever? Nine gender-neutral play kitchen picks

Without a doubt, one of the best gifts for a toddler turning two or three is a play kitchen.

9 easy steps to improve your baby photography

With a few simple tips you can take your images from random happy snaps to lovely clean images that create beautiful lasting memories.



What are your favourite baby products?

The Essential Baby Awards are on now, and we need your help! Have your say on your top picks and you'll go in the draw to win a share of $2500.

Essential Baby and Essential Kids is the place to find parenting information and parenting support relating to conception, pregnancy, birth, babies, toddlers, kids, maternity, family budgeting, family travel, nutrition and wellbeing, family entertainment, kids entertainment, tips for the family home, child-friendly recipes and parenting. Try our pregnancy due date calculator to determine your due date, or our ovulation calculator to predict ovulation and your fertile period. Our pregnancy week by week guide shows your baby's stages of development. Access our very active mum's discussion groups in the Essential Baby forums or the Essential Kids forums to talk to mums about conception, pregnancy, birth, babies, toddlers, kids and parenting lifestyle. Essential Baby also offers a baby names database of more than 22,000 baby names, popular baby names, boys' names, girls' names and baby names advice in our baby names forum. Essential Kids features a range of free printable worksheets for kids from preschool years through to primary school years. For the latest baby clothes, maternity clothes, maternity accessories, toddler products, kids toys and kids clothing, breastfeeding and other parenting resources, check out Essential Baby and Essential Kids.