Jump to content

ICSI - anyone have any experience


  • Please log in to reply
19 replies to this topic

#1 shells0701

Posted 06 April 2012 - 08:31 PM

Hi,

We are in the process of doing all the prelim police checks etc and hoping to start our first IVF  cycle in May. I was just wondering if anyone has done IVF with ICSI and if so what was the success of this vs the 'conventional' IVF?

We attended an info session the other night and apart from the cost diff which in the scheme of things is not that much more (I think $400) I was wondering why more people didn't go with this option...would appreciate any thoughts/advice?

#2 LoveMy3Kids

Posted 06 April 2012 - 08:38 PM

We did an ICSI cycle as we have male fertility issues. The sperm were spun off to remove the dodgy ones and then only good ones were injected into the eggs. This gave us the best chance of conception and we luckily achieved a positive on our first cycle.

I would think that if there are only female fertility issues that ICSI isn't necessary as the sperm will fertilise the eggs once given the opportunity.

Good luck with your cycle!

#3 Guest_Dinah_Harris_*

Posted 06 April 2012 - 09:11 PM

We did our ICSI in 2005 so was a while ago now.  From memory, ICSI was significantly more expensive.  This might have changed since then. We used it for male infertility.
ETA, as for success rates, we were always given 40% success rate.  I'm not sure how this rates against conventional IVF.

Edited by Dinah_Harris, 06 April 2012 - 09:13 PM.


#4 libbylu

Posted 06 April 2012 - 09:18 PM

When I looked into it 18 months ago it was about $1500 more expensive per cycle to do ICSI than conventional IVF.  We were initially going to do ICSI due to male factor issues, but our FS tested DSs sperm for zona binding and it was normal, so we ended up doing a conventional cycle.  
Our FS prefers not to do ICSI unless really necessary because you are taking away the natural selection element of fertilisation.  With ICSI, the embryologist chooses which sperm to inject into the egg based on properties that they can observe.  These are not necessarily the sperm that would normally make it into the egg.  When you do conventional IVF the sperm and eggs are all in the dish, so via natural selection, certain sperm beat the others too it.  He said we don't know what the long term affect of using ICSI will be.  However, so far there doesn't seem to be much difference but you are very slightly more likely to get a girl.
Good luck!

#5 Milano

Posted 06 April 2012 - 10:58 PM

QUOTE (LoveMy3Kids @ 06/04/2012, 08:38 PM) <{POST_SNAPBACK}>
I would think that if there are only female fertility issues that ICSI isn't necessary as the sperm will fertilise the eggs once given the opportunity.


Not true unfortunately. My DH has perfect swimmers and we are doing ISCI because I have Low Ovarian Reserve (ie. I'm a poor responder and don't get many eggs). Because of this, ICSI is recommended by our FS to help our minimal eggs get the best chance of fertilising.

#6 LoveMy3Kids

Posted 07 April 2012 - 12:07 AM

QUOTE (Milano @ 06/04/2012, 11:58 PM) <{POST_SNAPBACK}>
Not true unfortunately. My DH has perfect swimmers and we are doing ISCI because I have Low Ovarian Reserve (ie. I'm a poor responder and don't get many eggs). Because of this, ICSI is recommended by our FS to help our minimal eggs get the best chance of fertilising.


I wasn't aware of this. Thanks for clarifying  original.gif . I guess we only had explained to us the information we needed to know.

#7 EloiseIVF

Posted 07 April 2012 - 07:55 AM

Hi Shells,

I also have LOR, like Milano. I've just finished a long down reg cycle. We got 4 good quality eggs and DH's sperm also looked good in the dish, however none would penetrate the eggs so we got no fertilisations. I was told they will do ICSI next time, so I'm stimming back to back. I'm a bit angry that they didn't do it this time when they saw the sperm binding issue, especially since four good eggs for me was in itself a minor miracle. So, in short, we didn't actually have either egg quality or sperm quality issues; just some 'unexplained' non binding sperm. I would say ASK, ASK, ASK all you need to.

Ellie x

#8 emski72

Posted 07 April 2012 - 08:07 AM

We just did ICSI last cycle and $1k extra with City Fertility Clinic.

#9 Monket

Posted 07 April 2012 - 08:19 AM

We did ICSI in 2006 due to sperm binding issues.  FTR, we had a boy!

#10 causeway

Posted 07 April 2012 - 08:29 AM

We did ICSI with both our cycles & the outcome of our second cycle is wearing a green wondersuit, lying next to me. We were with QFG & once medicare rebate came back we were out of pocket by $40. BTW, we did have a girl... I didnt know that ICSI produced more girls! ICSI was recommended due to my LOR & poor numbers, as well as moderate DNA issues in sperm.

#11 Moo point

Posted 07 April 2012 - 08:32 AM

We needed ICSI due to male factor infertility. It was about $1500 more expensive on the initial outlay but we got a good portion back from Medicare (about $2.5k out of pocket per cycle).

From my understanding, it is more successful than conventional IVF for male factor, as the scientists are able to select the best looking (ie normal shape, normal movement) and inject one sperm into each egg. The downside to it is that it relies on them deciding out of a range of thousands or millions of sperm which few look the best. As PPs said, it is also good for issues such as low egg reserve or sperm binding or penetration issues.

We did two full stim cycles with ICSI, with an early loss on the second cycle, and were successful on our third cycle when we combined it with high digital magnification. This allowed the scientists to select only those sperm with no or small vacuoles (air bubbles in the head of the sperm) which cannot be seen on ordinary ICSI magnification and can indicate abnormality in the sperm/chromosomes. I am expecting a boy in 10 weeks original.gif

I have 3 sets of friends who conceived through conventional IVF for endometriosis/unexplained issues with no sperm issues, and another set who conceived through ICSI due to male factor. It is all dependent on your individual issues, and the first IVF cycle you do, whatever the recommendation, can be a learning curve for your specialists as they see how you respond to the treatment and how the sperm/eggs and embryos turn out. Best of luck, OP original.gif

#12 TinMan

Posted 07 April 2012 - 08:38 AM

We did ICSI because of MFI <failed VR>.

We had success on the fourth full cycle.

Good luck, it can be information overload at first.

#13 Brodes

Posted 07 April 2012 - 08:39 AM

My beautiful almost 4yr old daughter is a ICSI frozen blastocyst original.gif We had ICSI done because my husband had, had a vasectomy and his swimmers no longer swam wink.gif

Good luck with your IVF journey!

#14 librablonde

Posted 07 April 2012 - 11:41 AM

I've done ICSI since I started IVF, and am using frozen anon donor sperm.

#15 domestically~challenged

Posted 07 April 2012 - 12:10 PM

We had female factor and male factor and used ICSI.

We used ICSI as my DH's results weren't high enough to do IVF alone.

As mentioned above IVF is the preference as it allows for natural selection.

We had good fert rates with ICSI 11/11 feritlising and then 14/15. Unfortunately we still had to transfer 13 embryos to have success and I do wonder if it would of been sooner had we used straight IVF - quality over quantity and all that.

Best of luck with everything.

#16 specialone

Posted 07 April 2012 - 02:58 PM

Hi,

It only costs $300 for us to do ICSI through our fertility clinic (so not a lot of difference in cost).

We have male fertility problems (only small % mobile sperm).

My first IVF cycle we did a 50/50 split (something you could do?) - which is 50% ICSI and 50% standard IVF. We had 12 eggs to start with. With ICSI we got 4/6 eggs fertilised. With standard IVF we got 6/6 eggs fertlised.

For our second IVF cycle we decided not do do any ICSI as we had got such good fertilisation with standard IVF during our first cycle. Again had 12 eggs to start with. We got 4/12 eggs fertilised - a bit of a disaster... very disappointing. And none of the embryos were any good (none to freeze etc).

We are about to do third IVF cycle and specialist has recommended 100% ICSI which we are contemplating. We will definitely at least do 50/50 as had such low fertility rate for second cycle (only 33%).

Specialist said that on average you get about 60-70% fertilisation from ISCI. Which is better then the 33% we got last cycle without ICSI! We got 66% fertilisation from ISI during the first cycle we did.

I feel ICSI is a bit of a safety net.... makes me feel that we will at least get some embryos... We had such a bad cycle without ICSI in our second cycle that we aren't making that mistake again.

Good luck




#17 shells0701

Posted 07 April 2012 - 09:39 PM

Thank you so much all for your advice and sharing your experiences. The whole process has been very overwhelming to say the least and I fear it's going to get more so!
Our fs suggested Icsi because my husband has sperm antibodies so it's a preferred method.
Thanks again for the info - have learnt quite a bit

#18 jm3

Posted 07 April 2012 - 09:57 PM

QUOTE (libbylu @ 06/04/2012, 08:48 PM) <{POST_SNAPBACK}>
Our FS prefers not to do ICSI unless really necessary because you are taking away the natural selection element of fertilisation.


I didn't think of this at all when the FS suggested that ICSI had a better success rate.  My husband on the other hand said no way no how.  He said IVF is 'artifical' enough without having someone in a lab coat pick the best of each to go together.  Each to their own.

#19 specialone

Posted 08 April 2012 - 02:37 PM

Hi,

Well, I don't think there is much natural about IVF anyway... and if ICSI increases chances of pregnancy then I will go that way. Paying way to much money to lose out due to lack of fertilisation of eggs (like I had last time without ICSI).

Not much natural about making your body produce tonnes of eggs etc. My DH lets me makes most of the choices with IVF (he's happy to do whatever) as he knows its me that ends up going through most of the agony (after EPU I swell up like a balloon etc).

Even if you do natural IVF they still select the best sperm to put with the eggs (and hope that does the trick)... so its not exactly fully natural selection even that way. They weed out the bad looking sperm.

It would have been nice to not do ICSI but I will do whatever it takes to give us the best chance at pregnancy. I think (but will have to check) that my current 2 year old daughter was via ICSI.

All the best - I would go with what your specialist recommends - they know lots of stuff!

#20 NotBitzerMaloney

Posted 08 April 2012 - 03:00 PM

Our first cycle was straight IVF. I wasn't keen on ICSI .... Which changed rapidly when we only had a 20% fertilisation rate from round one (2/10)

Round two we did ICSI and had an 80% fertilization rate.

We ended up having two 5-days blasts from both stim cycles (1 fresh tfr and 1 to freeze), but I was still happy we went with ICSI for round 2 - especially as I got pregnant from that ICSI cycle.



2 user(s) are reading this topic

0 members, 2 guests, 0 anonymous users

 

Natural pain relief in the early stages of labour

While managing labour pains on your own can be daunting, there are a number of natural pain relief options to help you cope until you are admitted to hospital.

Chinese woman gives birth to quintuplets

After six years of trying for a baby, a couple’s dreams have come true many times over after the mum gave birth to quintuplets this week.

Five-year-old shoots nine-month-old brother dead

A nine-month-old baby boy died on Monday after he was shot in the head by his five-year-old brother in their grandfather's home.

'Is that baby yours?'

She is my daughter. I gave birth to her. I nurse her. But she doesn't have any of my genes.

Episiotomy in childbirth: not just 'a little snip'

Episiotomies have a place in maternity care – and can occasionally save lives – but should not be performed routinely.

Toddler aggression not caused by language delays after all: study

The logic was that children who don’t have the language to fully express themselves will lash out when they’re misunderstood. Not anymore.

Why we chose to adopt a child with Down sydrome

Everyone in foster care (and really in life) has something that makes them more vulnerable. We just know what our son's is.

Object of desire

Curvy mums make clever babies

Scientists appear to have discovered why women have evolved to have more curves than men – shapely thighs and bottoms lead to healthier babies.

'We'll make sure they know how much she loved them'

A first-time mum will never get to hold her four newborns, dying shortly after giving birth to the quadruplets.

The baby names NZ knocked back in 2014

A New Zealander has tried to name their baby Senior Constable but didn't get away with it - and numbering children is also a no-no.

How can you go into labour without knowing you're pregnant?

For most of us, the idea that a woman could carry a child to full-term without knowing she is pregnant is mind-boggling.

Will you get to the hospital in time?

Worrying your baby will be delivered by the roadside is a common concern for many mothers-to-be. So how likely are you to be caught short?

Video: Funny 'Lips Are Moving' parody just for mums

Meghan Trainor's song 'Lips Are Moving' was already a hit, but now it's been turned into a hilarious parody that is set to be very popular with frustrated mums everywhere.

Out with the clutter

Decluttering by the numbers: take the 30-day challenge

Forget the 5:2 diet - Twitter's 30-day declutter challenge will have your house back in shape in no time (well, a month).

Parents, don't be too hard on yourselves

We need to stop damning parents of today, and embrace their appetite for knowledge instead.

Is my baby normal?

There are chubby Buddha babies and there are thin, smaller babies. Neither are right or wrong, they are all 'normal'.

When an older sibling starts school

When one child goes to ‘big school’ and leaves the other behind, it can cause deep upset. Here's how to make the transition easier.

Stray cat saves abandoned baby

They say dogs are man's best friend, but one cat has proven felines can be just as devoted to their human companions.

How strangers are helping a mum's wish come true after her death

A mum of five, Liz Marquez wanted to breastfeed her premmie son for a year. So when she passed away suddenly, her friends - and strangers - stepped in to help.

Win an Octonauts prize pack

To celebrate the launch of Octonauts Live! Operation Reef Shield, a spectacular underwater adventure live on stage, we are giving away an amazing Octonauts prize pack to one lucky fan.

Download now: Essential Kids Activity Finder app

Got bored kids? Quickly find the best activities for kids wherever you are in Australia with the Essential Kids app.

 
Advertisement
 
Advertisement
 
 
 

What's hot on EB

Stars help save choking babies

It's an important lesson to learn, but one that busy new mums and dads might overlook until it's too late.

New Girl star Zooey Deschanel pregnant

Actress Zooey Deschanel is expecting her first child with her producer boyfriend Jacob Pechenik.

16 times 'dad reflexes' saved the day

Of course, in some cases they may be the ones who actually got their child into a precarious position in the first place, but we'll ignore that for now.

Couple's 'non-traditional' pregnancy announcement goes viral

Knowing you are not the father of your pregnant wife's baby would usually indicate a rocky relationship ahead for traditional parents.

The trials and tribulations of identical triplet newborns

Pip Donnelly is still playing spot the difference with her newborn identical triplets, Isabelle, Georgina and Frankie.

Win an Octonauts prize pack

To celebrate the launch of Octonauts Live! Operation Reef Shield, a spectacular underwater adventure live on stage, we are giving away an amazing Octonauts prize pack to one lucky fan.

Earthquake baby thriving five years on

Jenny Alexis is lucky to be alive after spending four days buried in the rubble of the 2010 Haitian earthquake, but now she's a thriving five year old.

Please don't say I'm lucky because I was adopted

On the one hand I was having a regular life with friends and sports and sleepovers and school. But I was also always wondering: Did my mother love me? What was wrong with me?

An open letter to non-parents who offer advice on child-rearing

Kitty, when you’re the parent of my child you’re welcome to wade in with an opinion – but until then, I’d prefer you to have a supportive ear and a glass of wine ready.

Couple arrested over baby gun video

A US couple faces charges after investigators say they found mobile phone videos showing the woman's 12-month-old daughter putting a handgun in her mouth.

NSW Health dumps 10-year limit on frozen embryos

A 10-year time limit on storing frozen embryos that were created with donor sperm has been dropped by the NSW government.

How my happy-go-lucky husband became a monster

Sharan Nicholson-Rogers watched her husband change from a happy-go-lucky police officer into an unpredictable man prone to violent and emotional outbursts.

Dads-to-be experience hormonal changes, too

Dads-to-be experience hormonal changes in line with their pregnant partners, a new study shows.

'They were just doing their job': mum of toddler killed in police chase gone wrong

"They were just doing their job. I feel so sorry for them. It is all just too sad."

Miscarriages to be formally recognised by NSW government

Women who miscarry will be able to obtain an optional "recognition of loss" certificate as a formal recognition of their often heartbreaking loss.

Cafe cubby house 'too noisy' for neighbours

Teenage parties, domestic disputes, or raucous late night pubs are the things that usually come to mind when you think neighbourhood noise complaints.

Dad films baby playing with snake

Most parents would not consider a snake an appropriate playmate for their baby, but a US dad who filmed his daughter playing with a python has defended himself against criticism.

Clever breastfeeding products

Check out this range of products designed to help make your breastfeeding journey more enjoyable, manageable and convenient.

Win with The Boxtrolls

To celebrate the release of The Boxtrolls on 3D Blu-ray, DVD & Digital with UltraViolet, we're giving you the chance to win a Boxtroll stationary package and DVD.

 

School Term 1

Get after-school care sorted

Wait lists too long at OSHC? Use www.findababysitter.com.au to meet local nannies now.

 
Advertisement
 
 
Essential Baby and Essential Kids is the place to find parenting information and parenting support relating to conception, pregnancy, birth, babies, toddlers, kids, maternity, family budgeting, family travel, nutrition and wellbeing, family entertainment, kids entertainment, tips for the family home, child-friendly recipes and parenting. Try our pregnancy due date calculator to determine your due date, or our ovulation calculator to predict ovulation and your fertile period. Our pregnancy week by week guide shows your baby's stages of development. Access our very active mum's discussion groups in the Essential Baby forums or the Essential Kids forums to talk to mums about conception, pregnancy, birth, babies, toddlers, kids and parenting lifestyle. Essential Baby also offers a baby names database of more than 22,000 baby names, popular baby names, boys' names, girls' names and baby names advice in our baby names forum. Essential Kids features a range of free printable worksheets for kids from preschool years through to primary school years. For the latest baby clothes, maternity clothes, maternity accessories, toddler products, kids toys and kids clothing, breastfeeding and other parenting resources, check out Essential Baby and Essential Kids.