Jump to content

ICSI - anyone have any experience


  • Please log in to reply
19 replies to this topic

#1 shells0701

Posted 06 April 2012 - 08:31 PM

Hi,

We are in the process of doing all the prelim police checks etc and hoping to start our first IVF  cycle in May. I was just wondering if anyone has done IVF with ICSI and if so what was the success of this vs the 'conventional' IVF?

We attended an info session the other night and apart from the cost diff which in the scheme of things is not that much more (I think $400) I was wondering why more people didn't go with this option...would appreciate any thoughts/advice?

#2 LoveMy3Kids

Posted 06 April 2012 - 08:38 PM

We did an ICSI cycle as we have male fertility issues. The sperm were spun off to remove the dodgy ones and then only good ones were injected into the eggs. This gave us the best chance of conception and we luckily achieved a positive on our first cycle.

I would think that if there are only female fertility issues that ICSI isn't necessary as the sperm will fertilise the eggs once given the opportunity.

Good luck with your cycle!

#3 Guest_Dinah_Harris_*

Posted 06 April 2012 - 09:11 PM

We did our ICSI in 2005 so was a while ago now.  From memory, ICSI was significantly more expensive.  This might have changed since then. We used it for male infertility.
ETA, as for success rates, we were always given 40% success rate.  I'm not sure how this rates against conventional IVF.

Edited by Dinah_Harris, 06 April 2012 - 09:13 PM.


#4 libbylu

Posted 06 April 2012 - 09:18 PM

When I looked into it 18 months ago it was about $1500 more expensive per cycle to do ICSI than conventional IVF.  We were initially going to do ICSI due to male factor issues, but our FS tested DSs sperm for zona binding and it was normal, so we ended up doing a conventional cycle.  
Our FS prefers not to do ICSI unless really necessary because you are taking away the natural selection element of fertilisation.  With ICSI, the embryologist chooses which sperm to inject into the egg based on properties that they can observe.  These are not necessarily the sperm that would normally make it into the egg.  When you do conventional IVF the sperm and eggs are all in the dish, so via natural selection, certain sperm beat the others too it.  He said we don't know what the long term affect of using ICSI will be.  However, so far there doesn't seem to be much difference but you are very slightly more likely to get a girl.
Good luck!

#5 Milano

Posted 06 April 2012 - 10:58 PM

QUOTE (LoveMy3Kids @ 06/04/2012, 08:38 PM) <{POST_SNAPBACK}>
I would think that if there are only female fertility issues that ICSI isn't necessary as the sperm will fertilise the eggs once given the opportunity.


Not true unfortunately. My DH has perfect swimmers and we are doing ISCI because I have Low Ovarian Reserve (ie. I'm a poor responder and don't get many eggs). Because of this, ICSI is recommended by our FS to help our minimal eggs get the best chance of fertilising.

#6 LoveMy3Kids

Posted 07 April 2012 - 12:07 AM

QUOTE (Milano @ 06/04/2012, 11:58 PM) <{POST_SNAPBACK}>
Not true unfortunately. My DH has perfect swimmers and we are doing ISCI because I have Low Ovarian Reserve (ie. I'm a poor responder and don't get many eggs). Because of this, ICSI is recommended by our FS to help our minimal eggs get the best chance of fertilising.


I wasn't aware of this. Thanks for clarifying  original.gif . I guess we only had explained to us the information we needed to know.

#7 EloiseIVF

Posted 07 April 2012 - 07:55 AM

Hi Shells,

I also have LOR, like Milano. I've just finished a long down reg cycle. We got 4 good quality eggs and DH's sperm also looked good in the dish, however none would penetrate the eggs so we got no fertilisations. I was told they will do ICSI next time, so I'm stimming back to back. I'm a bit angry that they didn't do it this time when they saw the sperm binding issue, especially since four good eggs for me was in itself a minor miracle. So, in short, we didn't actually have either egg quality or sperm quality issues; just some 'unexplained' non binding sperm. I would say ASK, ASK, ASK all you need to.

Ellie x

#8 emski72

Posted 07 April 2012 - 08:07 AM

We just did ICSI last cycle and $1k extra with City Fertility Clinic.

#9 Monket

Posted 07 April 2012 - 08:19 AM

We did ICSI in 2006 due to sperm binding issues.  FTR, we had a boy!

#10 causeway

Posted 07 April 2012 - 08:29 AM

We did ICSI with both our cycles & the outcome of our second cycle is wearing a green wondersuit, lying next to me. We were with QFG & once medicare rebate came back we were out of pocket by $40. BTW, we did have a girl... I didnt know that ICSI produced more girls! ICSI was recommended due to my LOR & poor numbers, as well as moderate DNA issues in sperm.

#11 Moo point

Posted 07 April 2012 - 08:32 AM

We needed ICSI due to male factor infertility. It was about $1500 more expensive on the initial outlay but we got a good portion back from Medicare (about $2.5k out of pocket per cycle).

From my understanding, it is more successful than conventional IVF for male factor, as the scientists are able to select the best looking (ie normal shape, normal movement) and inject one sperm into each egg. The downside to it is that it relies on them deciding out of a range of thousands or millions of sperm which few look the best. As PPs said, it is also good for issues such as low egg reserve or sperm binding or penetration issues.

We did two full stim cycles with ICSI, with an early loss on the second cycle, and were successful on our third cycle when we combined it with high digital magnification. This allowed the scientists to select only those sperm with no or small vacuoles (air bubbles in the head of the sperm) which cannot be seen on ordinary ICSI magnification and can indicate abnormality in the sperm/chromosomes. I am expecting a boy in 10 weeks original.gif

I have 3 sets of friends who conceived through conventional IVF for endometriosis/unexplained issues with no sperm issues, and another set who conceived through ICSI due to male factor. It is all dependent on your individual issues, and the first IVF cycle you do, whatever the recommendation, can be a learning curve for your specialists as they see how you respond to the treatment and how the sperm/eggs and embryos turn out. Best of luck, OP original.gif

#12 TinMan

Posted 07 April 2012 - 08:38 AM

We did ICSI because of MFI <failed VR>.

We had success on the fourth full cycle.

Good luck, it can be information overload at first.

#13 Brodes

Posted 07 April 2012 - 08:39 AM

My beautiful almost 4yr old daughter is a ICSI frozen blastocyst original.gif We had ICSI done because my husband had, had a vasectomy and his swimmers no longer swam wink.gif

Good luck with your IVF journey!

#14 librablonde

Posted 07 April 2012 - 11:41 AM

I've done ICSI since I started IVF, and am using frozen anon donor sperm.

#15 domestically~challenged

Posted 07 April 2012 - 12:10 PM

We had female factor and male factor and used ICSI.

We used ICSI as my DH's results weren't high enough to do IVF alone.

As mentioned above IVF is the preference as it allows for natural selection.

We had good fert rates with ICSI 11/11 feritlising and then 14/15. Unfortunately we still had to transfer 13 embryos to have success and I do wonder if it would of been sooner had we used straight IVF - quality over quantity and all that.

Best of luck with everything.

#16 specialone

Posted 07 April 2012 - 02:58 PM

Hi,

It only costs $300 for us to do ICSI through our fertility clinic (so not a lot of difference in cost).

We have male fertility problems (only small % mobile sperm).

My first IVF cycle we did a 50/50 split (something you could do?) - which is 50% ICSI and 50% standard IVF. We had 12 eggs to start with. With ICSI we got 4/6 eggs fertilised. With standard IVF we got 6/6 eggs fertlised.

For our second IVF cycle we decided not do do any ICSI as we had got such good fertilisation with standard IVF during our first cycle. Again had 12 eggs to start with. We got 4/12 eggs fertilised - a bit of a disaster... very disappointing. And none of the embryos were any good (none to freeze etc).

We are about to do third IVF cycle and specialist has recommended 100% ICSI which we are contemplating. We will definitely at least do 50/50 as had such low fertility rate for second cycle (only 33%).

Specialist said that on average you get about 60-70% fertilisation from ISCI. Which is better then the 33% we got last cycle without ICSI! We got 66% fertilisation from ISI during the first cycle we did.

I feel ICSI is a bit of a safety net.... makes me feel that we will at least get some embryos... We had such a bad cycle without ICSI in our second cycle that we aren't making that mistake again.

Good luck




#17 shells0701

Posted 07 April 2012 - 09:39 PM

Thank you so much all for your advice and sharing your experiences. The whole process has been very overwhelming to say the least and I fear it's going to get more so!
Our fs suggested Icsi because my husband has sperm antibodies so it's a preferred method.
Thanks again for the info - have learnt quite a bit

#18 jm3

Posted 07 April 2012 - 09:57 PM

QUOTE (libbylu @ 06/04/2012, 08:48 PM) <{POST_SNAPBACK}>
Our FS prefers not to do ICSI unless really necessary because you are taking away the natural selection element of fertilisation.


I didn't think of this at all when the FS suggested that ICSI had a better success rate.  My husband on the other hand said no way no how.  He said IVF is 'artifical' enough without having someone in a lab coat pick the best of each to go together.  Each to their own.

#19 specialone

Posted 08 April 2012 - 02:37 PM

Hi,

Well, I don't think there is much natural about IVF anyway... and if ICSI increases chances of pregnancy then I will go that way. Paying way to much money to lose out due to lack of fertilisation of eggs (like I had last time without ICSI).

Not much natural about making your body produce tonnes of eggs etc. My DH lets me makes most of the choices with IVF (he's happy to do whatever) as he knows its me that ends up going through most of the agony (after EPU I swell up like a balloon etc).

Even if you do natural IVF they still select the best sperm to put with the eggs (and hope that does the trick)... so its not exactly fully natural selection even that way. They weed out the bad looking sperm.

It would have been nice to not do ICSI but I will do whatever it takes to give us the best chance at pregnancy. I think (but will have to check) that my current 2 year old daughter was via ICSI.

All the best - I would go with what your specialist recommends - they know lots of stuff!

#20 NotBitzerMaloney

Posted 08 April 2012 - 03:00 PM

Our first cycle was straight IVF. I wasn't keen on ICSI .... Which changed rapidly when we only had a 20% fertilisation rate from round one (2/10)

Round two we did ICSI and had an 80% fertilization rate.

We ended up having two 5-days blasts from both stim cycles (1 fresh tfr and 1 to freeze), but I was still happy we went with ICSI for round 2 - especially as I got pregnant from that ICSI cycle.



2 user(s) are reading this topic

0 members, 2 guests, 0 anonymous users

 

What not to say to a new mum

Some phrases just pop out before you really think about them, but there are some things you should try to not say to a new mum.

Why I'm glad to be an indulgent granny

The phone calls started a couple of weeks ago. At about 5.30 each evening - if I am lucky - I will be greeted by a sweet, excited voice declaring: "'Allo Annie".

Is this the worst relationship advice ever published?

You sometimes have to wonder whether relationship/sex advice from magazines is designed to help or humiliate.

How you talk to your baby now can impact social skills later

People used to think that social skills were something kids were born with, not taught.

Three truths about C-section mums

Lately I've been thinking about the caesarean stories and the brave women who birth their children with strength and beauty.

Scientists predict when you should start a family

Scientists have calculated at exactly what age you need to start trying to get pregnant to have the best chance of realising your dream. 

Differently abled child

When 'protecting' a child is really a cover for judgement

Why are people so concerned for this happy child and his mother?

When toddlers have strange obsessions

When it comes to two-year-olds and birthday cakes there are a few requests that are usually at the top of the list. But a cake featuring a local personal injury lawyer?

When Mama Bear strikes

When we become mums, our instinct to protect our children and keep them safe from harm is so strong we're often likened to a Mama Bear protecting her cubs.  

Immunity boosters for kids

There are no guaranteed ways to avoid the dreaded winter illnesses completely, but there are ways we can boost our children's immunity.

Mum shares portrait of her proudly breastfeeding three-year-old

Jade Beall usually chooses to breastfeed her son, now 3, in private. This week, however, she shared portraits of her breastfeeding her preschooler.

Dealing with a toddler's morning tantrums

Your schedule is not important to your two-year-old, and you cannot convince her otherwise. So what can you do?

Child in suitcase 'could have died eight years ago'

A child whose remains were dumped in a suitcase in the South Australian bush is believed to have been a girl aged between two-and-a-half to four.

MP breastfeeds baby during parliamentary session

An Argentinian mum and politician has caused a stir on social media after being filmed breastfeeding her baby.

My baby's first seizure

It was 1am on a cold winter's night when I woke suddenly to the screams of my 12-month-old son. Our lives were about to change forever.

Portable pools 'more dangerous than permanent ones'

Inflatable and portable children's pools may be required to be sold with compulsory fencing to prevent backyard drownings, with some experts even floating the idea of a ban.

Heartbreaking moment mum kisses her one-week-old goodbye

At 11.07am on April 2 this year, Sarah Marriott welcomed baby Sebastian into the world.

The amazing Tee Pee bed and kid-friendly Frankie Bunk bed

These kids' beds definitely fit the brief of providing personality and personal space for little people who are moving up in the world.

The funny things kids say when you're pregnant

Since becoming noticeably pregnant, my son has taken more of an interest in the sibling he'll soon have.

The real problem with having one child

In this age of political correctness, it seems the one subject still subject to discrimination is that of the Only Child.

Six-week-old baby found dead, believed stabbed

A neighbour heard a child screaming before a baby was found dead, believed to have been stabbed, in a house in Newcastle.

The fire hazard in more than 70,000 Australian homes

So far, 206 Samsung washing machines have caught fire and some have exploded. But many remain in people's homes.

How having a baby can bring on OCD

We all know that having a baby can turn your life upside down - and it can also bring a raft of new anxieties and worries.

IVF gender selection being considered for Australian parents

Couples using IVF may be able to choose the gender of their babies and women could be financially compensated for donating their eggs.

The best age to get married (according to the latest study)

Not too young, and not too old. That's reportedly the best age to get married. Not everyone agrees.

Get your FREE Baby & Toddler Show ticket!

Get your free ticket to the Sydney Essential Baby & Toddler Show for September 25-27 - register online now.

 
Advertisement
 
Advertisement
 
 
 

What's hot on EB

Yes, you can get pregnant before your period returns post-baby

After giving birth, the last thing you want to think about is contraception. But you can get pregnant before your period comes back.

Fellow diner rewards mum after toddler's tantrum

Parents of toddlers everywhere know the feeling. After working up the courage to take your child out for lunch or dinner in public you are rewarded with a mid-meal meltdown. 

IKEA begins massive safety campaign after two toddler deaths

Two children were killed when pieces from their Malm furniture line tipped over.

Which beauty treatments are safe in pregnancy?

Is it safe to use fake tan, hair dye and nail varnish during pregnancy?

A dad's guide to hyperemesis

I am in no way qualified to advise women on how to cope with hyperemesis, but I've learnt some lessons that might be worth sharing with other partners.

The five ways I know my 'baby' is no longer a baby

The truth is, I can no longer deny that my walking, babbling, somewhat-independent little miss is no longer a bona fide 'baby'.

Woman adopts best friend's four daughters after cancer tragedy

Best friends share everything - and for these two life-long friends, that includes family.

Beaneasy: sweet nursery furniture with a twist

If you're looking to introduce an organic element into your baby's nursery but want to step away from natural timber, we have the perfect alternative.

Confirmed: men gain weight when they become dads

Men who become fathers experience weight gain and an increase in body mass index, a measurement of body fat based on height and weight, according to a new, large-scale study

Carer investigated over washing machine photo posted 'for a laugh'

She said the photo of a boy with Down syndrome in a washing machine was taken just for fun, but no one else was laughing.

The day my son started a fire

Would you know what to do in a fire emergency? How safe is your home and family?

Mum's premature labour nightmare after high tea salmonella outbreak

An opulent high tea at a luxury Melbourne hotel has left 44 people with salmonella poisoning - including a pregnant woman, who went into early labour.

The science of 'hangry': why some people get grumpy when hungry

Where does hanger come from? And why is it that only some people seem to get hangry?

What a baby with whooping cough sounds like

It's a heartbreaking video that anyone who has ever considered not vaccinating against whooping cough must see.

Couple's million dollar bill for premmie baby born on holiday

An Australian couple could face a medical expenses of more than $1 million after their baby boy was born three months prematurely while they were holidaying in Hawaii.

Coffee a day to keep disease at bay

Don't be surprised if your morning brew does more than wake you up. There's more to this magical elixir than you might think.

Why Prince George has 'two different looks'

Days out from Prince George's second birthday, his parents' tendency to dress him in classical style clothing has been revealed as a cunning ploy.

Husband films mum giving birth in moving car on freeway

An incredible birth video shows a mother delivering her own baby as her husband drives along a freeway in a vain attempt to reach hospital.

Breastfeeding while pregnant: is it safe?

Many women happily breastfeed well into pregnancy while others wean sooner; yet others continue to breastfeed both infants together. This is a personal choice.

Womb to world: transitioning your new baby

One minute they're contentedly snuggled in the sanctuary of their mum's tummy, and the next they arrive into an overwhelming reality of lights, cameras and action.

Gadgets

iSperm: the iPad home fertility test for men

A new gadget uses a tiny microscope and the camera on an iPad to calculate sperm count and motility.

The tiny twins who were strong from the start

I cried when a specialist told me at exactly 28 weeks that our twin boys would have to be born within 48 hours.

One day when I didn't know

Julia Watson, a mum of four young girls, was diagnosed with stage 4 bowel cancer in December 2013. She shares her latest blog piece with Essential Baby. 

 

FREE TICKET

See Pinky McKay live in Sydney

Get your free ticket to The Essential Baby & Toddler Show and save $20 - register online now!

 
Advertisement
 
 
Essential Baby and Essential Kids is the place to find parenting information and parenting support relating to conception, pregnancy, birth, babies, toddlers, kids, maternity, family budgeting, family travel, nutrition and wellbeing, family entertainment, kids entertainment, tips for the family home, child-friendly recipes and parenting. Try our pregnancy due date calculator to determine your due date, or our ovulation calculator to predict ovulation and your fertile period. Our pregnancy week by week guide shows your baby's stages of development. Access our very active mum's discussion groups in the Essential Baby forums or the Essential Kids forums to talk to mums about conception, pregnancy, birth, babies, toddlers, kids and parenting lifestyle. Essential Baby also offers a baby names database of more than 22,000 baby names, popular baby names, boys' names, girls' names and baby names advice in our baby names forum. Essential Kids features a range of free printable worksheets for kids from preschool years through to primary school years. For the latest baby clothes, maternity clothes, maternity accessories, toddler products, kids toys and kids clothing, breastfeeding and other parenting resources, check out Essential Baby and Essential Kids.