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5 miscarriages - need help


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#1 13Jassie13

Posted 02 April 2012 - 09:32 PM

Hi I have had 5 miscarriages (including 2 D&Cs) in the last 14 months. I have a 2 1/2 year old and had no problems conceiving her.  My OBs only advice has been to take low dose aspirin (after MC#3). No other tests or treatment. Because I am 43, it's assumedg that they are due to chromosomal abnormalities. But I have read that at my age, there is a 50% chromosomal abnormality rate, not 100%. I just can't believe that there is nothing else to be done. Can anyone offer advice, recommend a specialist or clinic in Melbourne please?

#2 minidiamond

Posted 02 April 2012 - 09:37 PM

I'm so sorry Michaela.

I'd be considering changing OBs, at worst he should've referred you to recurrent miscarriage clinic, assuming you haven't had any other testing.  I know there is one in Melb, I think attached to one of the universities.

Did you have testing on any of you D & Cs ? I had two and neither showed chromosome issues.  You're right, though, it's the case in about 50% of m/cs.

I'm sure you know the stats on older women being more likely to m/c but it sounds like you need at least a second opinion.

Good luck.

#3 Spring Chickadee

Posted 02 April 2012 - 09:43 PM

so your OB has done no tests? That is totally negligent IMO, especially given you age you need to be sorting out the issue asap.

There are a number of issues that can arise after your first child so it is definately worth testing. After the 3rd Loss the OB should have ordered a full panel of MC tests. my OB does this after only 2 losses.

Also, you previous losses from the 3rd onwards should have been tests to see if it was infact a chomosonal issue.

also, treating with asprin without any testing has been shown to cause implatantion issues. Aprin is only one treatment specific to one possible cause of MC. You may need thyroxine, progesterone, metformin, clexane or another medication instead which can be prescribed once you actually know what the issue is.

I would get a referral from a GP to see a Fertility Specialist asap. It can take around 4 weeks to do and get back all the tests, some are medicare rebatable and quite a few are out of pocket.

It may actually be something as simple as your thyroid. If it went out of whack after you first birth it may not be producing the hormones required to sustain a pregnancy.

I'm still a little shocked that your OB has allowed 5 losses to occur without testing.  ohmy.gif

Edited by Freckles, 09 April 2012 - 09:14 AM.
Sig removed by Moderator


#4 TwiceTheWoman

Posted 02 April 2012 - 09:46 PM

So Sorry Michaela.
I encourage you to please contact the Royal Women's Hospital information service for further guidance.....

http://www.thewomens.org.au/AskaNurseorMidwife

#5 13Jassie13

Posted 03 April 2012 - 01:49 PM

thanks for the replies. Extra info to add is that the 4th MC (i.e. 2nd D&C) was chromosomal. Currently I am in limbo because I am supposed to be 7 weeks pg but at 6 weeks nothing showed up on US not even a sac. My HCGs were 1000 and 1200 two days later. Just had message from OB to have another HCG today.  I know that 1000 at 6 weeks is way too low and not doubling so the PG has failed. But I have no cramping, bleeding, anything. So I don't know how long it will take to MC naturally, if I will need a D & C, if its ectopic. Going crazy! Rang the Royal womens this morning, thanks for tip!



#6 13Jassie13

Posted 05 April 2012 - 05:29 PM

Hi more developments!. My Ob rang today to say the levels are rising as they should! However it is only around 10000 and I am supposed to be 7 weeks 2 days. I have to have another U/S next week. OB was very non committal about what this may mean. Any ideas? Do I have any hope? Any experiences of slow to double/low HCGs that turned out Ok??

#7 Libster

Posted 05 April 2012 - 06:04 PM

I was in the same situation as you - my HCG levels were rising but not at the rate they should have been. My OB said that sometimes HCG can rise slowly and everything be fine however it is not very common. I unfortunately had a miscarriage, fingers crossed for you.

Edited by Mariamsmum, 17 June 2013 - 07:23 PM.
Edited by mariamsmum to remove signature


#8 Duechristmasday

Posted 07 April 2012 - 11:36 AM

Good luck and I hope this pregnancy works out for you.

I had 6 misscarriages in between baby number 3 and 4, it was awful.  No one in mainstream, medicine could figure out what was happening.  I went to the recurring misscarriage clinic at the womens hospital in Melbourne.  They just did a whole load of blood tests.  To be honest its such an awful clinic to go to.  It is set up in the pregnancy clinic area so when you are waiting to see the specialists you are sitting with all the pregnant ladies.... its not really very good.

Anyway, I had 4 D&C's during this time, and 3 of the 4 were chromosomal.  Strange given I was 37 at the time and had 3 healthy kids.....

went to a naturopath after trying everything else, and turns out I had toxins in my system that was affecting my vitamin B levels (we live on an old orchard where they sprayed loads of pesticides before banning them -  and moved in there about 6 months before I started misscarrying).  Also my progesterone was being affected because of the low vitamin B levels.  i took some drops, got rid of the crap in my system (1 month), and dosed up on Vitamin B and Voila 2 healthy pregnancies later.........

Happy to forward info to you, seriously this lady is fantastic and it does not involve a large $$ outlay and heaps of visits.  

Anyway good luck and I hope it works out for you.  Dont lose hope !  Start eating heaps of bananas and take vitamin B in the meantime.....

#9 13Jassie13

Posted 08 April 2012 - 07:10 AM

Started light bleeding on Good Friday - now having full on bleeding and cramping - at least I won't have to have a D&C (I hope). Have appointment next Fri with
OB - DH ready to grill about what else can be done. Would appreciate if Liltuss if you could PM me with details of the person you saw. Thanks everyone

#10 lilsunniegirl

Posted 08 April 2012 - 07:35 AM

Michaela3333, Im so sorry. just read your last post..

I agree with the PP, in that you should definitely seek further investigation and assistance.. after my 3rd MC, I had the full workup of BT to investigate why i might be mc'ing, hycosy, ovulation/progesterone levels monitoring via BT and US to view folicles, and plans in place for IUI should the next cycle fail. My DH also had his sperm tested as well..

I did go on the aspirin too, as well as TCM and acupuncture, higher dose folate..

Whilst age more than likely plays a role, there could be something else that is easily fixed via additional medication or intervention.

Be kind to yourself this easter and wish you all the best for your ttc journey

#11 13Jassie13

Posted 09 April 2012 - 08:02 PM

Thanks for your kind words. Ended up going to emergency as the cramping was bad - like mid labour! HCGs dropping which is "good"  but they were still worried about ectopic. Had a U/S and would you believe my rotten luck: two complex cysts on my left ovary!! What does this mean? Could this be the cause of my M/Cs???  Have to have more BTs to look at hormone/enzymes levels. Can't believe, it, not only another m/c but now this to worry about, if they need removing, will delay even more...

#12 13Jassie13

Posted 09 April 2012 - 08:06 PM

lillsunniegirl, did you succeed in the end?? Did they find a treatable cause for you Mcs?? Did you have any previous successful pregnancies? I'm assuming a lot of things are not being tested for (e.g. DH sperm) is because we have a child already so it must rule it out?

#13 lilsunniegirl

Posted 09 April 2012 - 08:23 PM

I did... i fell straight away following my 3rd miscarriage.. the first trimester was filled with bleeding and cramping, so it was a scary road.. but we got there. I was ready to give up too after 6 years, and Im glad I didnt.

I hadnt had a successful pregnancy leading up to Kai..

We never got anything ourselves conclusively from the testing.. all looked great.. textbook cycles, great hormone levels where they should be, follicles were great.. my DH had some clumping in his sperm so we got him on Blackmores Mens Performance, and he drank less, and no smoking.

One thing though, I think it had something to do with my bloodtype.. Kai was AbO incompatible (me o+ and him b+ - not rhesus negative, unlike that, you can prevent or treat this).. and they mentioned that can happen and might have a link to miscarriage..

I cant imagine it wouldnt hurt to still have a full suite of testing done.. you never know what can change in a persons body over a lifetime, before and after children..

I guess like the ones who struggle for years and years and years, then have a successful pregnancy, then fall very very easily again.. somewhere, something had changed..

Im not sure what the 'complex' means... when can they look into it further for you? I hope you are ok. PM any time.

#14 13Jassie13

Posted 09 April 2012 - 08:52 PM

That's great news that it worked out in the end despite not finding a cause. I'm trying to hold on to whatever little hope there is.  Love hearing these postive stories. My mum had twins at 43 and DH's mum had a baby at 45.

#15 minidiamond

Posted 09 April 2012 - 09:10 PM

Michaela catching up with your thread, I am so so sorry this has happened again, it is just beyond cruel.

Take care & I hope you begin to feel a bit better both physically & emotionally soon.

I should have mentioned, I am in Sydney so can't recommend a clinic but have heard good things about Royal Women's.  All my testing was through my IVF clinic, it included the 'standard' blood tests that I'm sure the recurring m/c clinic does, I also had an endometrial biopsy & at one stage was going to have PGD testing on our embryos, which is essentially weeding out the chromosomally abnormal ones.  As far as I'm aware, this is only done through IVF clinics (and is hugely expensive).

*****m/c & preg mentioned *****

In the end after two early m/c I got a BFP that seems to be sticking.  I was on clexane to stop clotting for the first trimester, and also prednisone (steroid), as something of a 'precaution' against natural killer cells, which came back borderline in bloods.  I am 22 weeks along today & turn 43 next week.

All the very best, I hope you can find some answers.

#16 Eirinn

Posted 09 April 2012 - 09:17 PM

QUOTE (Duechristmasday @ 07/04/2012, 11:36 AM) <{POST_SNAPBACK}>
went to a naturopath after trying everything else, and turns out I had toxins in my system that was affecting my vitamin B levels (we live on an old orchard where they sprayed loads of pesticides before banning them -  and moved in there about 6 months before I started misscarrying).  Also my progesterone was being affected because of the low vitamin B levels.  i took some drops, got rid of the crap in my system (1 month), and dosed up on Vitamin B and Voila 2 healthy pregnancies later.........

Happy to forward info to you, seriously this lady is fantastic and it does not involve a large $$ outlay and heaps of visits.


Could you PM me her name pretty please?

#17 13Jassie13

Posted 10 April 2012 - 01:58 PM

Hi Liltus

I'm really interested in the killer cell treatment. We asked our Ob about this after MC#4 but he was reluctant. We are ready to demand prednisolone at next appt - the research we've looked at says is experimental and has side effects but I want to try everything of course. Just these stupid cysts are worrying me know - I'm 44 in July so window is closing fast.

Have referral for Royal Women's but no appointment yet, think unlikely the public system will prescribe steroids though, I assume you got it privately?

#18 zjb2

Posted 10 April 2012 - 03:27 PM

Michaelan3333, Sorry to hear about all your losses.

I just wanted to add that I believe it is a good idea to do the full panel of recurrent miscarriage testing, because you just don't know what you may find.

I had 4 miscarriages aged 39/40. It was initially perceived that it was my age factor but during the testing a number of other causes were found. One was male factor and without treatment we were looking at a 100% chance of miscarriage. We ended up doing IVF for this factor and are now 22 weeks along at nearly 42 years of age (did use progesterone and clexane for the first 12 weeks to support the pregnancy).

We did go privately, the level of testing and treatment was fantastic and for us it was the best thing. Even if you decide to go the public route if you need any treatment, maybe it is worth considering a private FS that deals with miscarriage testing for an initial and a follow up appointment just for the investigation stage. I am not in Melbourne so can't suggest anyone in particular but if you want a Sydney FS I can recommend one. Good luck with your next steps.

#19 sulky11

Posted 10 April 2012 - 03:44 PM

QUOTE (Duechristmasday @ 07/04/2012, 11:36 AM) <{POST_SNAPBACK}>
Good luck and I hope this pregnancy works out for you.

I had 6 misscarriages in between baby number 3 and 4, it was awful.  No one in mainstream, medicine could figure out what was happening.  I went to the recurring misscarriage clinic at the womens hospital in Melbourne.  They just did a whole load of blood tests.  To be honest its such an awful clinic to go to.  It is set up in the pregnancy clinic area so when you are waiting to see the specialists you are sitting with all the pregnant ladies.... its not really very good.

Anyway, I had 4 D&C's during this time, and 3 of the 4 were chromosomal.  Strange given I was 37 at the time and had 3 healthy kids.....

went to a naturopath after trying everything else, and turns out I had toxins in my system that was affecting my vitamin B levels (we live on an old orchard where they sprayed loads of pesticides before banning them -  and moved in there about 6 months before I started misscarrying).  Also my progesterone was being affected because of the low vitamin B levels.  i took some drops, got rid of the crap in my system (1 month), and dosed up on Vitamin B and Voila 2 healthy pregnancies later.........

Happy to forward info to you, seriously this lady is fantastic and it does not involve a large $ outlay and heaps of visits.  

Anyway good luck and I hope it works out for you.  Dont lose hope !  Start eating heaps of bananas and take vitamin B in the meantime.....







Hi Duechristmasday: is is possible to also receive the naturopath contact details rolleyes.gif

#20 Madalem

Posted 10 April 2012 - 04:56 PM

QUOTE (Duechristmasday @ 07/04/2012, 12:36 PM)
went to a naturopath after trying everything else, and turns out I had toxins in my system that was affecting my vitamin B levels (we live on an old orchard where they sprayed loads of pesticides before banning them -  and moved in there about 6 months before I started misscarrying).  Also my progesterone was being affected because of the low vitamin B levels.  i took some drops, got rid of the crap in my system (1 month), and dosed up on Vitamin B and Voila 2 healthy pregnancies later.........

Happy to forward info to you, seriously this lady is fantastic and it does not involve a large $ outlay and heaps of visits...


Duechristmasday - could you pm the naturopath details as well please.... rolleyes.gif I've had 4 m/c, and have been seeing a naturopath, but would love another opinion. I'm also waiting for a PGD cycle in May...

Edited by Madalem, 10 April 2012 - 05:00 PM.


#21 13Jassie13

Posted 10 April 2012 - 07:31 PM

Hi zjp2

Congratulations on your pregnancy! Must be such a relief for things to finally go right. Is this your first pregnancy? I think that age is a disadvantage because there is a bias against us. It's like "what do you expect at your age" So I believe things have been slow to move because of this which is very ironic when time is of the essence. I did go on Clexane and progesterone for 4th pg but turned out to be chromosomal (that's the only one we know cause) so was doomed from the start.

Thanks for the info - if we get no joy, may be asking you for your contact in Sydney!

#22 13Jassie13

Posted 11 April 2012 - 04:19 PM

Went for BT for cysts today. Happened to look at the BT request form, and it said "CA 125" which of course I had to look up when I got home. It stands for "Cancer Antigen" and it is a tumor marker for ovarian cancer. Two days for results.....

#23 Jenflea

Posted 11 April 2012 - 04:28 PM

Good luck with the test results!

#24 13Jassie13

Posted 13 April 2012 - 11:16 AM

Saw OB today and can now start on Thyroxine and prednisolone next cycle. Said main side effects are bloating. Anyone have experience with this?

Passed intact 8 week old embryo and sent for testing - was very traumatic. I had been lucky to avoid a D & C but this was worse!

#25 13Jassie13

Posted 13 April 2012 - 12:56 PM

I have finally got a script for  prednisolone and thyroxine. Liltus, what were your side effects of taking the  prednisolone?

We asked our OB to tell us what tests he had done and turns out he had  done tests for a lot of things, he just hadn't told us any details. He  also said IVF and embryo screening wasn't an option for us because I  would have very few eggs at my age and also you can only screen for  specific causes, not general chromosomal issues.

Anyway we left feeling like we had exhausted all possibilities and now can start the steroids...


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