Jump to content

Anyone had a higher than expected DS risk at 12 weeks due to high HCG levels?


  • Please log in to reply
11 replies to this topic

#1 Tetinks

Posted 21 March 2011 - 04:49 PM

Hi

Hope my title made sense...

I am just over 14 weeks with baby #3. I had my NT scan last week at 13+2 and it all looked great - NT thickness was 1.5mm, we saw a nasal bone and the development is all on track - nothing unusual.

I saw my ob today and frustratingly, the lab sent him my blood results but have not yet provided a risk assessment as the software they use isn't working ( rolleyes.gif  don't even get me started on that!).

But he said that going by my blood results, I can probably expect a higher than expected risk. He said he wasn't too concerned, but not to expect a very low risk like I had with my older kids.

My PAPP-A was .78mom
My hCG was 2.15mom.

So the PAPP-A levels are okay, physically the baby looks okay, but my HCG is quite a bit higher than they would like.

I'm just wondering if anyone else has experienced this? What was your risk? I will hopefully get my combined risk tomorrow and will obviously decide then whether or not to get further testing. FWIW my hcg levels were very high in early pregnancy too - about 4-5 times the average on betabase.

Also, does anyone know why the hcg could be so high at this stage of pregnancy? Obviously Down Syndrome is a possible cause, but is there anything else?

Cheers.

#2 mylittlemen

Posted 21 March 2011 - 04:57 PM

Me.

My NT measurement was 2.3mm (so higher than yours but within the 'normal' range), my PappA was a shade over 1 (so normal) and my BHCG was a bit over 2 (I can't remember exactly now but about what yours is).

I got a 1 in 85 risk of DS (I will also be 36 when this baby is born).  I went on to have an amnio and have received the all clear.  My dr told me that while she could give me no certainty, her view was that it would be VERY unusual to be the 1 in the 85 if it was only based on elevated BHCG.  I was told the 'norm' was to have elevated BHCG and lower PappA as well.  However, this is a statistical test so you can't ever be sure one way or the other.

I did some google research and from what I could see, there is a slightly greater chance you are having a girl if you have an elevated BHCG at the NT scan time (although take that with a grain of salt as it was google research).  I couldn't find any other reason for it.

I do wonder if the elevated level was what caused my morning sickness to last until 20 weeks (vs about 13 weeks with DS).

Sorry you are going through this.  It was a very stressful time for DH and I.

#3 mylittlemen

Posted 21 March 2011 - 05:27 PM

While you are waiting for your results, you might want to have a play with the tool here:

http://www.sbpsoftware.com/trisomy-risk-calculator.html

However, please note that I was linked to it through another forum and everyone on that forum who used it (myself included) got better results using that tool than the official results we were given (not by much though) so don't be shocked if your official result is a bit 'worse'.  From what we could see, it depends on how the software weights the importance of the NT measurement vs. the blood test results.

Also, it may be completely unrelated but at 22 weeks, this baby is very large.  I have had a scan at 19 weeks which showed over 100 percentile on all measurements so had to have a GD check (came back all clear) and a further detailed scan with a specialist.  This confirmed the measurements (very large baby tracking nicely on its own curve for size - still over 100 percentile across the board) but there is no reason for it - they just think we've made a big baby this time (DS was 4.1kg so not exactly tiny and it may be my 2nd baby is bigger).

#4 TheSmithFamily

Posted 21 March 2011 - 05:37 PM

Hi there,

For my second pregnancy I got a high risk  1;99 but my fold was 3.2 and my bloods were around 2 for each reading.

After the amnio was all clear I had 2 scans at 20 and 22 weeks so they could do a very detailed heart scan as sometimes bloods can reflect an issue here, fwiw it was also a girl. all was okay.

Take care and I hope the results you get ease your mind at this stressful time.

Bron

#5 Angelina Ballerina

Posted 21 March 2011 - 05:50 PM

QUOTE (Expat2 @ 21/03/2011, 05:27 PM) <{POST_SNAPBACK}>
While you are waiting for your results, you might want to have a play with the tool here:

http://www.sbpsoftware.com/trisomy-risk-calculator.html

However, please note that I was linked to it through another forum and everyone on that forum who used it (myself included) got better results using that tool than the official results we were given (not by much though) so don't be shocked if your official result is a bit 'worse'.  From what we could see, it depends on how the software weights the importance of the NT measurement vs. the blood test results.

A



When I added 3 years to my age it was close to my actual results. It states the age risk as much lower than on my actual report

#6 Tetinks

Posted 21 March 2011 - 09:04 PM

Thanks everyone

I am feeling calmer about it all but very curious to get my combined risk assessment tomorrow. That link was interesting too.
QUOTE
My dr told me that while she could give me no certainty, her view was that it would be VERY unusual to be the 1 in the 85 if it was only based on elevated BHCG.

This is kind of what my dr said too... that the HCG was the least significant of the three results.

Will update tomorrow, hopefully.

#7 mrsmag09

Posted 22 March 2011 - 08:31 AM

Hi claireabell

When I had my nt scan at exactly 12 weeks, I was given a 1:460 risk of DS. This was based mostly on my very high hcg (almost 4!) because my papp-a was around 0.75 and the nuchal fold was 1.4mm. All my scans have looked normal since then so we are all HOPING and praying that the baby is ok. We decided against any invasive testing, but not a day goes by when I don't think about it...

Good luck with your results



#8 ~Sh3ekY M0nKeY TaMeR~

Posted 22 March 2011 - 08:38 AM

I am 29 my NT measurement was 2.7 my bloods were not unlike yours and I got a 1:27. An amnio has since proven there are no problems.

#9 Jessminder

Posted 22 March 2011 - 12:10 PM

Hi Clarebell,

My 12 week results are quite similar to yours -

NT - 1.60
Pappa A - 0.80
hCG - 2.36

However, my overall risk for DS came in a 1:6501, which suprised me because it was lower than my risk with DD 2 years ago. The Dr who performed the scan did mention that my hCG was higher than normal but he said that in isolation this doesn't cause any concern. I did have a missed mc the month before we conceived so I don't know if that contributed to the elevated levels.

Good luck for today.

#10 Tetinks

Posted 22 March 2011 - 04:49 PM

Thanks everyone

I got my risk today and it's 1:825, so not as 'good' as with my older 2 but still much better than I was expecting.

Jessminder I wonder why our risks are so different when our results are so similar. I see from your sig we are about the same age too (I will be 33 when this one is born).

#11 Jessminder

Posted 23 March 2011 - 12:41 PM

That's a very good question Clairebell. I would have thought that I would have a higher risk than you due to my hCG and NT being slightly higher. I had my scan done in the UK at the Fetal Medical Centre in London and they also take into consideration blood flow through a valve in the liver and the heart. I'm not sure if these factors are used over here but that is the only thing I can attribute to the difference in our overall results.






#12 Angelina Ballerina

Posted 23 March 2011 - 02:01 PM

claireabell that's great that you ended up with a low risk result after all




0 user(s) are reading this topic

0 members, 0 guests, 0 anonymous users

 

The day my daughter almost drowned

We had six adults standing there, so I felt like I could relax a bit. After all, what could go wrong with so much supervision?

Sydney siege survivor names baby after victim Katrina Dawson

A Sydney barrister who survived the Lindt cafe siege has named her newborn daughter after her best friend who died in the tragedy.

Banishing bloat

How to avoid a bloated tummy

Here are some foods to eat in order to escape feeling ghastly and gassy.

The great new picture book for anxious kids

My son is a worrier by nature. I learnt long ago that it was completely pointless to say to him "Don't worry about it!".

Budget stripped more than $15b from families

The combined impact of the two budgets for low and middle income people was "devastating", new analysis by the Australian Council of Social Service shows.

Pregnant women urged to get flu shots

As the winter chill starts to arrive, NSW Health is urging pregnant women to get their flu shots.

65-year-old gives birth to quadruplets

A 65-year-old German woman, who already has 13 children, has given birth to quadruplets.

What you need to know about pregnancy and health insurance

It's not just waiting periods that couples need to consider - there are other factors to consider when thinking about health insurance.

Yummy mummy

Nicole Trunfio breastfeeds baby on Elle magazine cover

Australian model Nicole Trunfio has taken the concept of multitasking to a fashionable new level for Elle Australia.

Warnings after baby girl died while sleeping in bouncer

Parents have been warned about the dangers of letting babies sleep in bouncers and swings following the death of a three-month-old girl.

Coping with fatigue as a parent

Sleep deprivation is a real hazard of caring for a baby. But there are ways to manage the challenges of fatigue better.

A very 21st century issue: parents, parks and smart phones

It's not all the parents, and it's not all the time, but there is often at least one doing it. And sometimes, that 'one' is me.

Appliances

Faulty washing machines linked to house fires

More than 80,000 faulty Samsung washing machines pose a fire threat in homes throughout Australia despite a nationwide recall of the machines.

'I had a lotus birth and I loved it'

Lotus birthing is not all that common, but for a number of women it feels like the most natural thing to do.

7 things you might not know about postnatal depression

Despite its widespread nature, there is still a great amount of mystery surrounding PND - and it's important to try unravelling as much of that as we can.

Is your family's car part of the world's biggest safety recall?

More than 50 million vehicles recalled for potentially lethal airbag fault - is your car affected?

Why drinking water can be deadly for babies

H2O is one of the necessities of life, but for babies a seemingly harmless amount of water can be fatal.

Mother-in-law faceplants during proposal

He had it all planned: a romantic proposal on a windswept beach. The whole family would be there so they'd all be able to celebrate the joyous moment together.

A preschooler suddenly goes mute - and it's not just shyness

When our son stopped talking, our sense of loss was painful and acute.

The mums who ask for a 'wife bonus'

They run their homes like domestic CEOs and work tirelessly to improve their family's social standing. And now, according to a new book, they want an annual perk from their husbands.

Woman shares photo of dimple on breast to warn others of cancer risk

A widely-shared Facebook photograph of a British woman's breast has raised awareness of a more subtle breast cancer symptom.

Starting a family despite a low sperm count

"I'd never really failed a test - how could I fail this particularly manly test?"

It's official: we must better protect our kids from toxic lead exposure

New guidelines have been released, aimed at reducing children's harmful exposure to lead. But they still don't go far enough.

Trouble-shooting toddler social skills

Chances are your toddler's behaviour is all completely normal - but here's how to tackle some common social problems.

Helping your first-born welcome a sibling

We did sigh with joy at the arrival of a royal princess - but, mostly, we sighed with pity at the sight of Prince George being taken to meet her.

Farewell, daytime nap

I've been in denial and I'm not too proud to beg, but it appears I must accept the fact that you have gone. I need to let you go.

The identical triplets who are one in 50 million

The father of identical triplets born in a Texas hospital says his three daughters, including conjoined twins, are "a miracle" sent by God.

Seven questions you should be asking about your health cover

If the last time you assessed your health cover was five years ago, there?s a chance it may no longer suit your needs. To ensure it?s still right for your family, click here for seven questions to ask.

 
Advertisement
 
Advertisement
 
 
 

What's hot on EB

How to use gas effectively in labour

Many women in labour don't use gas effectively and suffer more side effects than benefits. Here's how to get the most out of this pain relief option.

'He has gastro but that's okay, right?': sick kid etiquette

We cannot place all children who are sick in a bubble till they recover, but we can give other parents a choice about exposing their kids to them.

Ada Nicodemou: 'I can never be completely happy again'

Home and Away actress Ada Nicodemou has opened up about the loss of her stillborn baby.

10 things to consider when you're thinking about trying for a baby

Before you start tracking your menstrual cycle and reading up on the best positions to get pregnant, there are a few other things you may want to consider.

How special surgery and IVF can create a post-vasectomy baby

Cricket legend Glenn McGrath and his second wife Sara are expecting their first child together, thanks to IVF and a delicate surgical sperm retrieval process that helped the couple to conceive.

Belle Gibson's mother 'disgusted and embarrassed'

The mother of disgraced wellness blogger Belle Gibson has accused her daughter of lying about her childhood in an attempt to garner public sympathy.

Doctor's mobile phone 'left inside c-section mum'

A new mum claims a doctor left his mobile phone inside her after delivering her baby via caesarean section.

I'm a mum and I'm following my dreams

I want my kids to know that no matter what happens in life, you can still be who it is that you've always wanted to be.

Those first daycare days

I had this innate 'mum' moment the other day.

'If one person had listened, my life would have been so different'

Katherine's father will die in prison for the horrifying sexual abuse of his daughter. Yet she is the one with the true life sentence.

This new plan undermines breastfeeding and baby health at everyone's expense

Mothers, babies, the health system and the wider society are going to pay the price of this new budget.

Couple to celebrate terminally ill baby's birthday in unique way

Baby Jai Bishop has lived at Starship Hospital for the past seven months, with his parents flying back and forth from Hokitika, 1100km away, to be by his side.

Life On Mars

It's men who need 'retraining', not women

We are all responsible for our own behaviour. Telling victims to harden up is wrong.

Baby Gammy's dad tries to claim charity money

The biological father of baby Gammy has reportedly tried to access charity money raised for the little boy's medical costs.

Where are the childcare places?

It?s all very well to encourage women to work if they choose to, but how can the measures lead to increased workforce participation when women are once again left holding the baby?

The pain of not having babies and not knowing why

After seven years of wishing, hoping, crying, punching pillows and shouting "why me?!", the end result is more than I ever thought possible.

Getting your family finances in order

Whether you're after a new car for a growing family, a bigger house, or are just fixing up your finances, here are the basics on borrowing.

Mum shares graphic selfie to warn against tanning

A mum has shared a graphic photo of her skin cancer treatment as a warning to others.

Does parenthood make us happier?

We can certainly gain higher levels of happiness when we become parents, but the trick is to not get overwhelmed by the pressures of raising our kids.

No, having a dog is not like having a human child

It's obvious these people dote on their pets, but they're barking up the wrong tree.

 

Top baby names

Baby Names

The numbers are in and we can now bring you the 2014 top baby name list for Australia.

 
Advertisement
 
 
Essential Baby and Essential Kids is the place to find parenting information and parenting support relating to conception, pregnancy, birth, babies, toddlers, kids, maternity, family budgeting, family travel, nutrition and wellbeing, family entertainment, kids entertainment, tips for the family home, child-friendly recipes and parenting. Try our pregnancy due date calculator to determine your due date, or our ovulation calculator to predict ovulation and your fertile period. Our pregnancy week by week guide shows your baby's stages of development. Access our very active mum's discussion groups in the Essential Baby forums or the Essential Kids forums to talk to mums about conception, pregnancy, birth, babies, toddlers, kids and parenting lifestyle. Essential Baby also offers a baby names database of more than 22,000 baby names, popular baby names, boys' names, girls' names and baby names advice in our baby names forum. Essential Kids features a range of free printable worksheets for kids from preschool years through to primary school years. For the latest baby clothes, maternity clothes, maternity accessories, toddler products, kids toys and kids clothing, breastfeeding and other parenting resources, check out Essential Baby and Essential Kids.