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clexane during pregnancy

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#1 kazza66

Posted 01 February 2007 - 08:58 PM

I was prescribed Clexane shots during my pregnancy. I have had clots in my lungs before and they are worried it will happen again. The leaphlet in the box said it hasnt been tested on women so they cant say whether it will harm the baby. The Dr seemed to think it was safe. I have read things for and against it. I wondered had anyone used it in there pregnancy? I am 5 weeks along.

#2 Angelblue71

Posted 01 February 2007 - 09:48 PM

Sorry, I am not able to assist, however ppl on EB have mentioned a phone service called Mothersafe (sorry I don't know the details) you could give them a call they might be able to answer.

Good luck and try not to worry because often the stress of wondering if something is bad for us is worse than the thing itself, I know-easier said than done.

#3 *~*

Posted 01 February 2007 - 10:01 PM

I'm 9 weeks pregnant and Clexane has been discussed for me to use as well.  Both my OB and renal physician have said that there is no harm to the baby.  The main problem is that it leaches calcium from the bones, so osteoporosis might be a problem down the track.  There is a buddy group for Clexane and Warfarin users - Go to Meet other Members, then EB buddy groups.  At least that way you can chat to others who have used it.  I find the whole thought of it a little daunting to be honest.


#4 Haute Mama

Posted 02 February 2007 - 03:21 AM


I have one friend who has lupus and had a baby recently after having clexane shots all the way through her pregnancy, her baby seems fine. She uses my OB of choice and I don't believe he would put her baby at any unnesssary risk.

I have another pregnant friend who has previously suffered severe pre eclampsia (twice before) and is having daily clexane shots as her PE seems to be clotting related.  She also has a fantastic docotr - who I haven't personally used but have heard very ethical comments about.

I can't say if the clexane is safe, I have no human medical training at all, but I doubt these docotors would create risks for the baby if the risks to the mums weren't greater.

Do you trust your doctor?


#5 Gagsmissus

Posted 02 February 2007 - 06:28 AM

Hi Kazza66,

I am currently having 40mg Clexane injection daily. I have been on this since about 8 weeks pg. I am taking this as a preventative measure as I ended up with a DVT ( deep vein thrombosis) in my upper leg after my C/S with DS. I wear a support stocking as well but some days that can be unbearably uncomfortable

I discussed this with both my obstatrician(sp?) and heomotologist(sp?)-Blood doctor. I will need to have a bone density test after the twins are born as long term use does affect bone density. I also need to have monthly blood tests to check blood platelet levels.

I also rang Mothersafe ( Sydney at Royals womens hospital I think but I can't find the number, sorry) and they said there is no adverse affect for either pregnancy or breastfeeding. I was on 160mg Clexane for 3 months while breastfeeding DS.

Buddy group for clexane or warfrin users is here....
Clexane and Warfrin Users Hope that works..

Hope some of this helps..

Congratulations on your pregnancy!!!!!

#6 sarah326

Posted 02 February 2007 - 08:34 AM

Congratulations on your pregnancy,

I was on 40mg clexane injections for the first 14 weeks of my pregnancy b/c I have had 2 miscarriages and tests found that I have a moderate anti cardio lipin levels. (some blood clotting thing that I still don't understand 100%)

My obs sent me to a miscarriage management clinic and the Dr there prescribed the clexane and assured me that there was no problem taking it during pregnancy to the baby or the mother.

Good luck with your pregnancy.

#7 Star276

Posted 02 February 2007 - 09:42 AM

I was also on 40mg clexane from the time I found out I was pg to approx 13 weeks.  As per Sarah326, it was due to my 2 previous m/c - they thought that thinning the blood may assist in keeping the pg going.  I was also on 1 x cartia low doese aspirin each day and still am - I am now 34 weeks.  These were both prescribed by my fertility specialist and my OC was happy for me to continue.  All is well at my end!

#8 deanna29

Posted 02 February 2007 - 11:06 AM

I am currently taking 40mg a day of Clexane as well.  When I was 22 weeks pregnant with my now nearly 12 month old baby I had a pulminary embolism in my left lung.  I had to go onto clexane 80mg twice a day until I was 36 weeks pregnant and then 40mg a day until bubs was born.  My baby is fine and has never had any health problems.  I had to go back onto clexane the day after he was born for six weeks and then they put me on warfarin.  I fell pregnant (not planned) whilst on warfarin and am now back on Clexane again until this bubby is born.

I have been reassured by all my doctors that it is fine to take the clexane and will not hurt baby.

Please look in the buddy group for clexane/warfarin users as I found them to be a great help to put my mind at ease.

#9 NewLifeDirection

Posted 02 February 2007 - 01:13 PM

Hi there!

I am also on Clexane 40mg as a preventative this time around (as well as to help baby to stick) I have been on it since I git a BFP and will continue until 6 weeks post-partum.  (With a break over the labour).  

Last PG when they found a DVT I was on 120mg Clexane for 3 months and then 60mg for another 6 weeks (post-partum).  No major ill effects.

I discussed this everything with my heamatoltogist last Wednesday and he suggested blood tests at least every 6 weejks to check blood platelet levels as well as for some rare condition that people can develop white blood cells to act against the clexane and prevent it from working.  His view was that it was safer to be on CLexane during PG, if you have a history of DVT's, then to not be and have it happen again.

I am also a participant in the Clexane/Warfarin group so feel free to come and join us.


#10 kazza66

Posted 03 February 2007 - 11:15 AM

Thank you SOOOOOOOOOOO much for all the replies. You have helped put my mind at ease about it. I am going to start the Clexane today. I will also come and join the buddy group biggrin.gif

#11 beck *

Posted 11 April 2012 - 04:09 PM


Im currently 22 weeks pregnant and on 40mg of clexaine injections daily, i have a blood clotting disorder having found out after our baby girl Evie was born sleeping at 41 weeks.
I was wondering if anyone else has the prothrombin gene and MTHFR and has gone on to have a healthy baby using the clexaine injections,  im just a bit concerned about complications during labour such as lossing to much blood due to the blood being to thin, ive heard that you cant have an epidural and if you need an emergency c-section you have to be knocked out. thanks for your time Beck*

#12 KHK

Posted 11 April 2012 - 07:58 PM

Hi Beck,

I have a clotting disorder called factor five and lost our first son Kobi 2 years today at 38 weeks.  I was on aspirin which I stopped at 35 weeks during this pregnancy.

I have gone on to have another son who is almost 12months and was on aspirin and clexane 40mg during and after this pregnancy.  He was born prem at 34 weeks I had to stop the injections for 48hours before the c-sect and then I was back on them for 6 weeks.  My delivery was going to be planned anyway at 37weeks at which point I was to be induced or c-sect so that they could conrol this.  I was also on some serious monitoring from 28 weeks of my preg.

I am now 18 weeks preg again and I am on 60mg clexane this time around.  Again I am expecting a planned delivery at 37weeks if I make it that far.

If you want any more info just PM me.

Good luck.

#13 beck *

Posted 11 April 2012 - 08:59 PM

QUOTE (KHK @ 11/04/2012, 07:28 PM) <{POST_SNAPBACK}>
Hi Beck,

I have a clotting disorder called factor five and lost our first son Kobi 2 years today at 38 weeks.  I was on aspirin which I stopped at 35 weeks during this pregnancy.

I have gone on to have another son who is almost 12months and was on aspirin and clexane 40mg during and after this pregnancy.  He was born prem at 34 weeks I had to stop the injections for 48hours before the c-sect and then I was back on them for 6 weeks.  My delivery was going to be planned anyway at 37weeks at which point I was to be induced or c-sect so that they could conrol this.  I was also on some serious monitoring from 28 weeks of my preg.

I am now 18 weeks preg again and I am on 60mg clexane this time around.  Again I am expecting a planned delivery at 37weeks if I make it that far.

If you want any more info just PM me.

Good luck.

thankyou for your reply, im so sorry to here bout Kobi, i wish you all the very  best.  Did the doctors advise you to stay on the injections the whole way through the pregnancy, they have said that my levels are good and i could probly go off the injections if  i like, but i have decided to stay on them just for peace of mind im scared if i go of them things will go wrong again, its just extremly hard wondering what if again, there monitoring me every 3 weeks at the moment hopefully they will see me every fortnight soon, every week would be nice, may i ask why your little boy was prem. Thankyou once again for your time and all the best

#14 misse10

Posted 11 April 2012 - 09:29 PM

I was on clexane for the first 16 weeks of my pregnancy (currently 34 weeks). Mine is an ivf baby and. Was told its standard procedure as it reduces the risk of miscarriage and my doctor was a specialist in that. I was told there's no risk and so far everything seems fine!

Edited by misse10, 11 April 2012 - 09:30 PM.

#15 mez70

Posted 11 April 2012 - 09:43 PM

Bek I have clotting issues and a few antibodies etc thrown into the mix and have 3 kids from 2 pregnancies.
With regards to Ceasars yes it can rule out Epis however some anethestisits will allow a spinal block so you can remain awake especially if you have had 24-48 hours notice to stop the Clexane.

I was under a haemotologist the first time around and he strongly advised me to have an elective ceasear as he felt that any blood loss would be easier to manage and control though it was up to me. I was intending on a ceasar regardless.

Pregnancy 1 ended up in an emenrgency C section at 31 weeks due to a heamorraghe, Placent Previa and pre term labor. I had been having problems by that stage though for 3 weeks and 1 of my twins growth had slowled dramatically so from 28 weeks I was on notice it could be any day.....

Pregnancy 2 was managed without Haemotologist (thank goodness) and we were on Clexane the entire way through. was due to stop at 38 weeks with a ceaser booked for 38 and 2 however I went into Labor at 37 weeks and had another Emergency C section. With both they were generals and both I was given the option of Spinals. Also I don't know if it was because it was 8.00 o'clock at night and quiet but DH was actually given the offer to come in and watch once I was out of it with DS2 (trust me very rare with ceasars under gA but he declined lol)

Post birth I was on Cleaxne for 6 weeks as well
good luck

#16 WibbleWobble

Posted 11 April 2012 - 09:48 PM

Hi Beck I have the gene as well. I never had Clexane but took Asprin for two of my pregnancies up to 36 weeks. Post birth I was on Fragmin for 6 weeks.

Both times I was induced so that the birth could be monitored closely as my Obs did not want me to go into labour spontaneously. Has your Obs discussed this with you?

I hope the remainder of your pregnancy goes smoothly.

Edited by WibbleWobble, 11 April 2012 - 09:50 PM.

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