Jump to content

Prog pessaries vs Crinone

  • Please log in to reply
17 replies to this topic

#1 UniKitty

Posted 29 June 2006 - 10:39 PM

I am starting my first medicated FET cycle soon and have been prescibed prog pessaries. Unfortunately *TMI* they irritate my 'whatzit' pretty much straight away and leave me with shocking thrush  blush.gif . So when I was told I need to use them 3 times a day for up to 10 weeks, I just groaned  <_< . Yes, rectal application was suggested but I just can't bring myself to do it!!!

So now I am looking for an altenative. During my last IUI cycle I was on a double dose of Pregnyl injections in the 2ww instead of pessaries, but obviously I don't have that choice this time.

Can anyone tell me about Crinone:

How often do you apply?
How is it applied?
Have you had a reaction of any kind?
How much does it cost?
Anything else you can think of???

Are there any other alternatives ie injections, tablets, skin patches??

Thanks in advance

Edited by Duffa, 29 June 2006 - 10:40 PM.

#2 A32

Posted 29 June 2006 - 11:18 PM

Two words Jodes - paper mache. When you try them you will know what I mean.

Seriously though, I used them for my stim cycle and I inserted them once or twice a day (can't remember it was so long ago - sad). They are not as strong as the progesterone pessaries and not as slimey IMO. They don't leak out like the progesterone pessaries do. I didn't have a reaction but about five days after using them I had the paper mache effect. I was like.... what the hell is that up there?! It seemed to turn into paper.

Not sure how much they are but surely they are not as expensive as the $60 per week progesterone. After 14 weeks of pessaries twice daily over the past 8 months I am completely and utterly over them.

PIO shots (progesterone in oil injections) are not available in Australia anymore I believe. I asked about them too.

Good luck. Let me know how it goes.

#3 Little~Oggy

Posted 30 June 2006 - 07:04 AM

Jodes it won't actually be thrush most likely it would more likely be a reaction to the coconut oil they place on pessaries.
The main thing with crinone it the cost involved. Also taking a latcos bifficlous (sp? sorry) tablet during treatment would help if it does turn out to be thrush.
Personally I found crinone much better!.......Amber would have had to pay a small foruntue on this stuff because nearly all FETS!

#4 AlyV

Posted 30 June 2006 - 07:11 AM

Hi Jodes,

I haven't used the pessaries, but have just finished on the Crinone. I inserted them twice a day and found that I had to wear a panty liner as there was some discharge (love the paper mache comment!). I also experienced external itching but no thrush. Can't think of anything else sorry. I have used the Pregnyl in the past and found that I had terrible cramping with it.

All the best.

#5 jules095

Posted 30 June 2006 - 08:46 AM

Hi Jodes

I never had pessaries, so I can't comment on them.

I had Pregnyl for my 2nd stim cycle & liked it, becuase it was less fuss. The only thing is, it delayed AF by a couple of days, getting my hopes up.

For stim #1 & #3 I used Crinone. So I'll try to answer some of your question.

How often do you apply?

I used it once a day, but I have heard of people using it twice a day.

How is it applied?
It's a cream like substance, in an applicator. You just insert  it, then squeeze the top to release the Crinone.

Have you had a reaction of any kind?
I had cramping & sore (*)(*)s. It also (by the leaflet inside the packet), gives you a feeling of sadness & unworthiness.

How much does it cost?
Not really sure, but it was included in the cycle costs.

Anything else you can think of???
As the girls have said, there is a bit of leakage. I didn't have a problem until about 4 or 5 days after I started to use it. Then it started to come out.

Crinone delays AF for some people, but I got AF right on time (both times sad.gif )


Jules xoxoxo

#6 Nut

Posted 30 June 2006 - 09:14 AM

I have not used crinone but from what I have come across it is more expensive... Other than that I can't offer much info there.

One thing you could try if willing is to use the Pesseries anally rather than vaginally. Many others have done it and claim it to be less messy, more appropriate for day time applications (doesn't leak as much so the rest time is reduced) and won't cause thrush...

#7 sebela

Posted 30 June 2006 - 10:49 AM

I HATED crinone, gave me awful cramps and headaches, much preffered pessaries and found the mess factor to be fairly equal...

#8 AnotherFeral

Posted 30 June 2006 - 01:06 PM

For my last medicated FET, my FS said Crinone was too expensive, even though I had some irritation from the pessaries sad.gif. He didn't think the absorption would be adequate if I used them rectally (I know blood P4 levels can be higher from rectal application of the pessaries, but I guess he meant absorption into the endometrium). FS didn't want me using the injections either, as apparently they can have nasty effects at the injection site & sometimes cause infections.

#9 ellejaye

Posted 30 June 2006 - 02:46 PM

Hey Jodes

I had Crinone for my 2WW, and 'Messaries' as I call them suck!  But I guess we can't get through without them so here's what I recon...

How often do you apply?
I used it once a day, just as I was getting into bed so no problems with leaks during the day.  This was until 5ish days after I started and I got a small amount of discharge (kinda like paper mashe as amber said before) but nothing a small pantie liner didn't fix.

How is it applied?
It's in a tube (like those tampons with the applicator) with a little square at the end that holds the cream.  You insert it all the way up and squeeze the square with the cream a wallah done.

Have you had a reaction of any kind?
I was positive I was pregnant apart from the BFN HPT's.  Sore boobs, mild cramps, emotional, nausous etc but these are normal reactions.

How much does it cost?
No idea coz mine was included in the cycle cost.

Anything else you can think of???
Not really.  They weren't that bad, but hey if you're feeling up to doing the deed do it "BEFORE" you apply LOL
Oh and to follow on from Jules...Crinone did delay AF for me (hence thinking I was P).  I got to 14dpo still no AF (she's usually here by 12dpo for me) and AF didn't arrive until 3 days after I stopped applying them.

HTH original.gif

Edited by ellejaye, 30 June 2006 - 02:48 PM.

#10 misty_3

Posted 30 June 2006 - 04:12 PM

hi there, everyone pretty much sumed up about the crinone, but it is very expensive, im still using it and i finish my last one this saturday, but at my clinic its $150 for a box of 15. and you can not claim it back of medicare, and i use 1 a day for about 10 weeks.
the only thing that i hate is the discharge, with me it mainly comes out when i go to the loo, sorry if tmi, its kinda like a dry cottage cheese or a wet mushed up paper  blush.gif

#11 beccababy

Posted 30 June 2006 - 04:30 PM

I am on my 8th week of progesterone pessaries and I cannot tell you how much I HATE them.

For a start most if it seems to end up in the toilet and I'm sure it's not healthy for our waterways to have all these hormones getting into the foodstream (I bet I'm causing boobs in male fish or something...).

Even when you do 'stick them up your bum' which the nurse so tactifully suggested it still comes out!!

I can't wait to finish them but you have to wean yourself off them as your body gets used to them. From eight weeks the placenta starts making its own progesterone THANK GOD.

I know I should be grateful I still have a reason to take them but gee wiz they are annoying!

#12 shangobunni

Posted 30 June 2006 - 04:39 PM

I hated crinone so i used "messaries" I had to use 4 a day for 14weeks.. but hey ofcourse its worth it either way.

Crinone is equal to 3 pessaries so costs the same as 3 pessaries... at my clinic anyway..

Good luck  smile1.gif


#13 Nut

Posted 30 June 2006 - 04:47 PM

I have just started using them again... Progesterone was really good and I thought I would be fine with out them but it started dropping...

was rather disappointed when I was told to go back on 2 a day...

#14 StillRoz

Posted 30 June 2006 - 04:56 PM

Gees - $150 for 15 crinone seems an extreme price for a clinic to charge.
I ran out of crinone over Christmas/New Year and had to hunt around to get some on Dec 31st! My clinic was closed, the FS was uncontactable and no other doctor seemed to have any idea how to get any. A registrar at RWH managed to track some down for me at a pharmacy in Merrylands, but was unable to get the proper authorisation (from PBS in Tassie I think) to give me some special script (so that PBS would cover some of the cost). I had to pay the full "private" amount for crinone - which was $90 for 15. Clinic should be charging less than this as they obviously have the authority to prescribe it.

Also re. crinone .... it seems with pessaries that people are advised to lie down after use to help it get absorbed. My clinic gave very strict instructions when using crinone to use it at the end of the day, after shower and toilet, and then to walk around for 1 hour. It seems that something about the walking around helps it be absorbed. I didn't get much 'leakage' (just had to remove some 'paper mache' when having a shower blush.gif ) despite taking it daily for 8 wks. My progesterone level was always really high on crinone (~16dpo ... p4=500+).
If I was doing it all again, I would definately go with crinone again.
All the best

#15 beabea

Posted 30 June 2006 - 05:26 PM

Just a thing - I got that itch the first FET cycle with pessaries but it doesn't seem to be happening this time around, for some reason.  More deft at applying/cleaning up after?  Body decided not to react the same way?  Dunno.  But if you decide to stick with them, don't be too afraid...

#16 Little~Oggy

Posted 30 June 2006 - 06:32 PM

I've got to agree with Roz here....I reckon pessaries are way worse for leakage factor than crinone. The crinone sort of sits in place more.......and here's the STMI!

Cotton tips work great at clearing the little lumpies of cottate chesse that start fallling out on their own.

Roz I'm not sure what happens with non-ed cycles using crinone but I know with a ed they give you there first box PBS covered but then from there on in it doesn't get covered because there is somethng in the PBS that states it must be with the womans own egg.


#17 UniKitty

Posted 01 July 2006 - 01:40 AM

Thanks to everyone for the replies!

It seems there are positives and negatives for both systems. I think I am going o ask my F/S about using Crinone because I really want to avoid the irritation and extreme itching caused by the pessaries. I also like the idea of not having to lie down after application because it is not an option at my work for the midday dosage.

I guess if the Crinone is a problem I could always swap back???

Oh and has anyone managed to claim Crinone or Pessaries under pharmaceuticals through their health insurance (especially MBP)?

You know when I first started the whole ART roundabout, I always thought having to inject myself would have to be the worst thing ever. Now I actually find injections the easiest aspect of treatment  wacko.gif ! Syneral sniffing and pessaries are much much harder to deal with and really affect my day to day life.

Does anyone else think the same or am I just weird??

#18 Little~Oggy

Posted 01 July 2006 - 06:21 AM

Jodes I claimed my back through HBA and got like a huge $20 back from about $180. I even tried to see what the laws where in regards to importing it through USA. The main issue there being none of the companies would send it, from memory there is some legal clause about it being okay to bring it in for personal use but none of the US compaines will do it.


1 user(s) are reading this topic

0 members, 1 guests, 0 anonymous users


Newborn baby found in a nativity scene

Police are trying to trace a woman who abandoned a baby boy in the manger of a church nativity scene.

Life would be harder without my kids

The Humans of New York Facebook page is well known for sharing touching, real stories from one of the world's biggest cities – and it's just hit the heart of parents everywhere.

Mum dresses as Wonder Woman for last day of chemo

A Brisbane mum dressed up as a superhero to celebrate the end of her chemotherapy and created a moment her family will remember forever.

How a raisin can predict a toddler's IQ

All you need to assess a child's future intelligence is a plastic cup and a raisin, according to new research.

Former Hi-5 member's cannabis hope

Former Hi-5 star Tim Harding hopes a cannabis-derived drug will help control his daughter's epilepsy, which sees the four-year-old suffering between 50 and 100 seizures a day.

The top 5 reasons your toddler throws a tantrum

Whilst to the outside world little people may appear to have it easy, it's actually not always the case – just ask any toddler who's had their toast cut up the wrong way.

Glenn McGrath thought he'd lost his wife and baby

Australian cricket ledged Glen McGrath has spoken about the moment he thought he might lose his wife, Sara and their baby daughter, Madison.


Inside my Centrelink nightmare

Mother Bec Smith has been trying for months to access Centrelink payments. A "serious error" is preventing her.

Warnings over push for hourly childcare billing

Australia's peak childcare body has called for caution around the Turnbull government's push for childcare centres to charge parents by the hour, not by the day.

Cate Blanchett thought about adopting for years

Cate Blanchett says her recent adoption of a baby girl had nothing to do with wanting a daughter after having three sons.

Kate Walsh: 'I can't have kids'

Grey's Anatomy star Kate Walsh has revealed she is unable to have children because she has experienced early menopause.

The parasite that could boost fertility

The Tsimane women of Bolivia are often revered as among the most fertile in the world - on average having 10 children in their lifetimes -- but some are even more fertile than others.

Family may sue cousin over genetics

A Melbourne couple is suing the Royal Children's Hospital for failing to diagnose a genetic disorder in their first child - an error they allege caused them to have another child with severe disabilities.

Strange things mums have done in labour

While most women in labour focus on the upcoming birth of their baby, some women do more interesting things.

Michael Clarke reveals baby's name

When Michael Clarke said he was wrapped around the finger of his little princess, he wasn't joking.

The logistics of breastfeeding twins

Our life is more or less divided into neat four hour parcels of time and it's hard to get much of anything done in the time between feeds.

How to stop people ruining Christmas

We can make a conscious effort about how we react to those curly Christmas day scenarios that can send us up the wall, or should we say chimney.

Lots of formula offers for desperate mum

The mum who was down to her last three tins of baby formula said she had received hundreds of calls and offers to send her formula.

Surviving breast cancer while pregnant

It was last thing Rebecca O'Donnell expected at 30 weeks' pregnant. One morning, while putting on her bra, she felt a pea-sized lump in her right breast.

Cot sheet brands for the nursery

With so many awesome cot sheet options these days, we thought we'd put together a list of go-to brands for you to seek out for your baby's bed.


What's hot on EB

How I survived breast cancer while pregnant

It was last thing Rebecca O'Donnell expected at 30 weeks' pregnant. One morning, while putting on her bra, she felt a pea-sized lump in her right breast.

Grieving father's letter to Bataclan terrorists: "...this little boy will threaten you by being happy and free"

A grieving father whose wife was killed in the attacks on the Bataclan Theatre last weekend has written an open letter to her killers.

5 challenges of motherhood - and how to see them differently

Despite the smiles, the sloppy kisses and the pure magic children bring to our lives, it's hard to deny that motherhood can be tough.

4 challenges of being a new dad - and how to face them

Becoming a parent is challenging – and that applies to both mums and dads.

My battle against antenatal and postnatal depression

I was five months pregnant when I realised I needed help.

Children swapped at birth will not be returned to biological parents

A boy and girl accidentally swapped on the day they were born will stay with the families who have raised them, a South African court has ruled.

A quarter of men believe they get 'man periods'

A British study has revealed one in four men believe they have a monthly cycle.

Baby deposit

How much do you need to save for a 'baby deposit'?

It's fairly straightforward to calculate a house deposit, but how much money do you need to save up for a baby?

Dad's beautiful note to his wife, a nurse

To anyone else it might just look like a picture of a mum having a nap with her toddler.

'I was a complete schmuck': Mike Baird opens up about his wife's postnatal depression

When his wife Kerryn was not well following the birth of their daughter, NSW Premier Mike Baird buried himself in his work.

Mum's desperate plea as whooping cough alert issued

A desperate mother has shared a heart-breaking video of her baby struggling to cope with a coughing fit caused by pertussis.

Coffee could help you live longer

New US research found people who report drinking three to five cups of coffee a day are less likely to die prematurely from heart disease, suicide, diabetes or Parkinson's disease.

The joy and dread of playdates

To live vicariously through your child is to rediscover anxieties you thought dead and buried.

Sick baby could die without scarce special formula, mum says

Lizzie Cann is down to her last three tins of a special formula in short supply.

Adorable toddler's strop foiled by squeaky shoes

We're probably all familiar with the pouty bottom lip and tightly crossed arms of a tot mid-strop.

More sex during World Cup created more baby boys

More sex during South Africa's World Cup meant a disproportionately high number of boys were born nine months later, a new study has found.

Win one of two ABC Shop prize packs in time for Christmas

What a boon it would be to have your toddler's Christmas gifts covered this year. We have two awesome ABC Shop prize packs to give away to two lucky winners.

Do fitness challenges really work?

Fitness challenges aren't new. There's Michelle Bridges 12WBT and a bunch of other programs if you really want to lose weight.

What are pregnant women Googling?

Pregnancy is a huge change for any woman, so it's natural we'll have questions - and turn to Google to ask them.



Can't decide?

Check out the Essential Baby Names section for some inspiration

Essential Baby and Essential Kids is the place to find parenting information and parenting support relating to conception, pregnancy, birth, babies, toddlers, kids, maternity, family budgeting, family travel, nutrition and wellbeing, family entertainment, kids entertainment, tips for the family home, child-friendly recipes and parenting. Try our pregnancy due date calculator to determine your due date, or our ovulation calculator to predict ovulation and your fertile period. Our pregnancy week by week guide shows your baby's stages of development. Access our very active mum's discussion groups in the Essential Baby forums or the Essential Kids forums to talk to mums about conception, pregnancy, birth, babies, toddlers, kids and parenting lifestyle. Essential Baby also offers a baby names database of more than 22,000 baby names, popular baby names, boys' names, girls' names and baby names advice in our baby names forum. Essential Kids features a range of free printable worksheets for kids from preschool years through to primary school years. For the latest baby clothes, maternity clothes, maternity accessories, toddler products, kids toys and kids clothing, breastfeeding and other parenting resources, check out Essential Baby and Essential Kids.