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Reflux - ? Losec not working

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#1 Rainbow17

Posted 14 February 2017 - 03:20 AM

Hi there,
I am desperately after some advice & help. Sitting here with my eyes stinging from lack of sleep.

My 12 week old has been on Losec for weeks now. Well over 6 weeks. He has been on the compounded version but I'm beginning to wonder if it is even working or if he has something else wrong with him??

I can't decide if he has silent reflux & the Losec isn't working or if he has severe colic? All the symptoms run into each other.

I'm thinking of changing his Losec medication from the compound mixture, but wanting some advice. What have others used & found to be more effective?
Any advice ASAP would be greatly appreciated


#2 Tired & Nasty

Posted 14 February 2017 - 05:56 AM

My understanding is that Losec doesn't stop the reflux , it just stops acid production so it doesn't burn when it does come up the throat.
Less acid production does also mean that less comes up too.

i also found buying the tablets , cutting and dissolving in a small amount of water  works better than the mixture made by chemists.

Edited by Tired & Nasty, 14 February 2017 - 05:58 AM.

#3 Ellie bean

Posted 14 February 2017 - 06:05 AM

Cutting and dissolving worked better for us too- the quality of the compound depends on who makes it and often the mixture isn't effective for long
Give it at least 20 mins before a feed if possible, also it worked better for us splitting the dose into 2 doses at 12 hour intervals
What dose is he on? You may need a higher dose, or something like Zantac
What are his poos like? Any explosiveness/ frothiness? Reflux often (not always) goes hand in hand with dairy and/ or soy intolerances. You could speak to your dr about cutting out some foods (if bf) or switching formulas (if ff)
Have you tried raising the head of the cot?
Swaddling helped mine sleep a bit- love to dream swaddles were awesome
Even typing this takes me back to those hideous days- hang in there, I'm sure you're d a great job

#4 Ellie bean

Posted 14 February 2017 - 06:06 AM

Also, colic just means unexplained crying- if Drs trot out "colic" to you as if it means something, just remember it doesn't and ask for a better explanation

#5 sophiasmum

Posted 14 February 2017 - 07:08 AM

From memory (long time ago as DD is now 13.5) we tried losec first & then ended up on zantac. Once we reached the 6 month mark she improved A LOT.

#6 MrsLexiK

Posted 14 February 2017 - 07:08 AM

We put our youngest on nexium.it worked so much better for him. He still wasn't a great sleeper mind you but he became a happy baby.

#7 Prioritising Pooks

Posted 14 February 2017 - 07:58 AM

There is great advice here and other paths to try. How is feeding going? Does baby vomit? Hang in there, there's hope.

#8 Rainbow17

Posted 14 February 2017 - 09:25 AM

Thank you all so much everyone.  
My son is on 2mg/ml having about 1.5ml twice a day. The solution is from our local pharmacy who say they "compound" but i don't actually think it's a true compound like a Sydney pharmacy.
I have read some mothers prefer dissolving Losec tablets even though it tastes horrible for the baby.

Yes we have tried tilting his cot, swaddling. I have also cut out dairy/wheat in my diet.
His poos are quite explosive & often have some mucous in them. He is exclusively BF.
At night time it is like he is only happy & settled if he is on the breast or sleeping on my chest.
He is usually a pretty "happy" baby but just doesn't sleep (as soon as you put him down he wakes), and is extremly fidgety & rigid while feeding.
Screams in the car & pram also 😩😩😩

Has anyone used the compounded solution from a real compounding pharmacy??

Thanks 😊

#9 EmmDasher

Posted 14 February 2017 - 09:46 AM

We used to get the compounded solution from our compounding pharmacy but our Paediatrician was very against it. The liquid compound is not particularly stable. The shelf life is only about 3 weeks and it's hard to tell when it loses effectiveness until you have a screaming banshee again. It's more expensive and tricky to get a hold of.

We switched to the tablets. We dissolved them in a little water and spoon fed them to DD. Babies aren't conditioned to appreciate taste so she never cared about that and took it without issue.

The dosage your baby is on seems quite low. DD started on 5mg/day but by 3 months had progressed to 2 x 10mg doses per day. She weaned off the losec at 6months.

Edited by EmmDasher, 14 February 2017 - 09:47 AM.

#10 RichardParker

Posted 14 February 2017 - 09:53 AM

I had a lot of success with losec - but just half a tablet dissolved in a few mLs of water and given orally via a syringe, twice daily.  But that was for diagnosed (with a camera down his throat) severe reflux.  DS got to liking the taste of it and I found it settled him well.  I still give it to him occasionally even though the paed said it doesn't really work like that - that you should give a regular dose consistently to keep the acid in the stomach at a level that won't burn him.

Anyway, my (totally non-medically-trained) understanding is that losec either works fairly quickly or not at all.  That is, if the problem is reflux then losec should fix it, and if it's not working, then it might be something else.

The other thing I thought of when you were talking about frothy poos is lactose overdose.  This happened with my DS1 when I kept swapping breasts, and all he got was the watery fore milk, and none of the fattier hind-milk.  So I started feeding him for two or three feeds on one breast before changing sides - he ended up getting more of the fattier hind-milk and was fuller and more settled, and the frothy poos calmed down.  Maybe you could try that.

Hang in there - you're doing a great job and those early days are so tough.  It won't be like this forever, I promise.

Edited by RichardParker, 14 February 2017 - 09:56 AM.

#11 EmmDasher

Posted 14 February 2017 - 10:05 AM

I missed the bit about the mucousy stools. It would be worthwhile going back to a GP for further investigation & a medication review (type & dosage).

If you get a proper intolerance/allergy review then it will save you restricting yourself unnecessarily.

#12 Ellie bean

Posted 14 February 2017 - 10:11 AM

My DD was on 20mg a day too from about 3 months, that dose is quite low (assuming of course the problem is reflux)
It was only a combo of elemental formula and the humigh dose of losec that resulted in improvement for her but she was pretty extreme, if your baby is generally happy you hopefully wont need to go that far
Agree with pp about looking into lactose overload

#13 chicken_bits

Posted 14 February 2017 - 01:37 PM

When DD was 5 months we ended up with a referral to a Paed because the meds the GP was able to prescribe weren't doing anything to help her (she was vomiting 10 or so times a day and was screaming for hours at night). She was put on a stronger dose of Zantac and it was magic. She was able to come off it around 9 months once she was sitting/standing.

#14 ms mel

Posted 14 February 2017 - 04:16 PM

As others have said already, check the dose. It should be nearer to 5-10mg twice a day. The compounded version must be stored in the fridge and have the pH checked to get the longest expiry date possible. That is still usually 3 to 4 weeks max. Chat to your doctor about changing the dose or changing the medicine.
All the best. I survived a reflux child but only just.

#15 lucky 2

Posted 14 February 2017 - 07:10 PM

Would you consider seeing a LC, she could take a full feeding history, observe a feed and sharecinsights if she has any!
Its unknown if it can help at 12 weeks but it might. :)

#16 Furfeathersfleece

Posted 16 February 2017 - 05:31 AM

Zantac is what helped my ds1. Might be worth a try?

#17 Cheerful Prancer

Posted 16 February 2017 - 07:03 PM

Zantac worked well for us. I think we had to increase the dose 3 times between 7 weeks and 6 months because of weight gain.

Sleep schools can also help. When I was in one 75% of the babies were already on reflux meds of one kind or another. Some of them had their doses adjusted/ medication changed.

Good advice from PPs

You will get through this.

#18 Ellie bean

Posted 16 February 2017 - 10:53 PM

Hope things are okay OP

#19 IamtheMumma

Posted 16 February 2017 - 11:09 PM

We did the half tablet losec tablet dissolved in a couple of mls of water twice a day. 2mg sounds like a really low dose. I thought starting dose was 10mg? I also used gaviscon for the the first few weeks to help keep on top of the acid reflux. After that time had passed and DS was more upright, I dropped the gaviscon and just stayed on losec. I think he came off it around his first birthday.

I second seeing a lactation consultant.

#20 EmmDasher

Posted 17 February 2017 - 08:21 AM

 IamtheMumma, on 16 February 2017 - 11:09 PM, said:

We did the half tablet losec tablet dissolved in a couple of mls of water twice a day. 2mg sounds like a really low dose. I thought starting dose was 10mg? I also used gaviscon for the the first few weeks to help keep on top of the acid reflux. After that time had passed and DS was more upright, I dropped the gaviscon and just stayed on losec. I think he came off it around his first birthday.

I second seeing a lactation consultant.

The OP's dose is 1.5ml twice a day and the concentration is 2mg/ml. That's 6mg per day. The starting dose was around 5mg when my DD was diagnosed.

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