Jump to content

IVF breakthrough article


  • Please log in to reply
12 replies to this topic

#1 blackcat12

Posted 09 February 2013 - 12:55 PM

Just read this and thought it was worth posting, I was skeptical as its in the daily telegraph but on reading it seems legit.

The link

Edited to fix link!

Edited by blackcat12, 09 February 2013 - 01:09 PM.


#2 cordyline

Posted 14 February 2013 - 07:27 AM

Very interesting and sounds like a good step forward.

They say they have improved the culture that embryos are grown in before transfer to keep them alive. Hopefully this helps to avoid the devastating scenario where a couple goes through an egg collection and yet have no surviving embryos to transfer after 3 or 5 days.

Although based on the claims it Seems to me that this culture would improve the # of healthy embryos from each cycle rather than improve the chance of pregnancy from each embryo transfer. as the article states.

Or maybe the culture itself makes the surviving embryos "fitter & healthier" thus increasing the chance of pregnancy. Either way it is good that they are making improvements. Might stop a lot of multiple embryo transfers.

#3 domestically~challenged

Posted 17 February 2013 - 07:43 PM

QUOTE
DIAGNOSED with polycystic ovarian syndrome in her late teens, Sally Eagle was warned she might have a hard path to pregnancy.

After six-months of trying naturally, the 28-year-old Sydney woman met with Dr Mark Bowman and the team at Genea. She was one of 673 patients invited to join the clinical trial of a new solution which increases the likelihood of pregnancy per embryo transfer by 26 per cent.

Now six months pregnant, the 28-year-old said she was "lucky" the advances in IVF have allowed her to reach her goal of motherhood.

"I'm six months pregnant and can't believe it," she said.

"We are so lucky to have access to this technology."

The couple are expecting their baby in June this year.

"When I decided to start trying for a baby I knew there could be complications. It is hard because you do feel like you have failed," she said.


Someone in their 20's with PCOS who only TTC for 6 months naturally before moving on to IVF was a "successful" participant/statistic?

I wonder what the criteria was to be eligible for this trial. Those who already had a high chance of conception maybe...

Was quite excited about this research but not so much now.

#4 DragonsGrace

Posted 20 February 2013 - 11:16 AM

I was part of this trial and I believe all patients were eligible. I was told half of the eggs were put in the normal growth medium and half would be put in the new medium. There was to be no difference as to which embryos would be selected for implant/freezing. It was just to see if there was a better fert/survival rate with the new medium

Efs

Edited by DragonsGrace, 20 February 2013 - 11:17 AM.


#5 LittleListen

Posted 20 February 2013 - 11:26 AM

I was informed about this trial as I was eligible (simply had to be a patient undergoing IVF at this clinic and under the supervision of one of the participating doctors - they wanted a broad scope). I did not go ahead with IVF during the trial period, but Dr. Bowman is extremely conservative in his approach to the use of IVF and the clinic has been moving towards improving outcomes in single embryo transfer for some time.

I think overall it is a very positive move.

And FWIW - being in your 20's and only TTC for 6 months can occasionally mean that IVF is your only option. As hard as that is for some to believe  rolleyes.gif

EFS

Edited by eyesabove, 20 February 2013 - 11:27 AM.


#6 jules095

Posted 20 February 2013 - 12:22 PM

QUOTE (eyesabove @ 20/02/2013, 12:26 PM) <{POST_SNAPBACK}>
And FWIW - being in your 20's and only TTC for 6 months can occasionally mean that IVF is your only option. As hard as that is for some to believe  rolleyes.gif
That depend on what her reasons for infertility were.

If she was only told that PCOS in her teens would stop her conceiving, then why after only 6mths TTC at 28, did he go straight to IVF? Why not try cycle tracking, clomid, AI, etc, before it?

I agree with DC here.


#7 spring_rain

Posted 20 February 2013 - 12:33 PM

Apparently it does make the embryos cultured in it stronger and healthier. Even though I am over 40, I was offered the trial as well. for my first cycle I didn't take it however, the solution was used for the frozen transfer I had this morning. Our blastocyst thawed very well using the new solution and seemed to be robust when it was transferred.  As DH and I already have   a naturally conceived child, were were told from the outset we would only be eligible for single embryo transfers, and I don't think our doctor does multiples except under exceptional circumstances.  

Hopefully the 2ww will pass quickly.  Good luck to others TTC

#8 MrsLexiK

Posted 20 February 2013 - 12:46 PM

QUOTE (domestically~challenged @ 17/02/2013, 08:43 PM) <{POST_SNAPBACK}>
Someone in their 20's with PCOS who only TTC for 6 months naturally before moving on to IVF was a "successful" participant/statistic?

I wonder what the criteria was to be eligible for this trial. Those who already had a high chance of conception maybe...

Was quite excited about this research but not so much now.

My dr didn't even have me trying for 6 months before he was ready to move me onto IVF.

QUOTE (jules095 @ 20/02/2013, 01:22 PM) <{POST_SNAPBACK}>
That depend on what her reasons for infertility were.

If she was only told that PCOS in her teens would stop her conceiving, then why after only 6mths TTC at 28, did he go straight to IVF? Why not try cycle tracking, clomid, AI, etc, before it?

I agree with DC here.

Whilst I had PCOS my bloods and indicated that clomid and the like would not have been much good.  Also is it possible that naturally trying actually meant "naturally" trying, as in she very may well have done low intervention but that doesn't make for a good story does it.  

What about the 45 year old mother who has a 12 week old now and also a 2yr old.

QUOTE
New mum Lorraine Scholl, 45, thanks the scientists at Genea for the gift of her 12-week-old son Jimmy.

After six failed embryo implantations she joined the Genea trial of the new formula: "I met my husband when I was 39.

"We tried for 12 months naturally and then used IVF."

The Scholl family were overwhelmed to learn the first transfer was a success and the pair had a daughter, Jaida, now aged two.

"When I decided to start trying for a baby I knew there could be complications. It is hard because you do feel like you have failed," she said.

"I am grateful and very excited."



#9 LittleListen

Posted 20 February 2013 - 12:48 PM

QUOTE (jules095 @ 20/02/2013, 01:22 PM) <{POST_SNAPBACK}>
That depend on what her reasons for infertility were.

If she was only told that PCOS in her teens would stop her conceiving, then why after only 6mths TTC at 28, did he go straight to IVF? Why not try cycle tracking, clomid, AI, etc, before it?

I agree with DC here.



I agree. It absolutely depends on what the reasons for infertility were. The PP has no way of knowing that either. I find blanket statements about those of us in our 20's 'rushing' into IVF unhelpful - sometimes there are genuine reasons.

Why is is that the general community (and the usually supportive EB community) insist on blanket statements regarding timelines for these things? How are we to know what the circumstances are. This woman's treatment could have involved months and levels of AC that are undisclosed in the article prior to the patient undertaking the IVF attempt. It doesn't even specify that the successful attempt was her first IVF cycle either.  

Genea has only offered the study to those who have agreed with their doctor to try IVF for whatever reason - not the other way around. Given that their goal is to increase the statistics on successful first time attempts of IVF leading to full term/live birth pregnancies, (and yes, to increase their market share by being seen as a successful clinic) - how is this development a disappointment for the PP?

#10 LittleListen

Posted 20 February 2013 - 12:49 PM

Further information found here:

http://www.genea.com.au/Success-Rates/New-...o-Culture-Media

#11 DragonsGrace

Posted 20 February 2013 - 02:21 PM

I have PCOS but that had nothing to do with why we had to do IVF. I was on Metformin which got me pg twice with both ending in mc which were caused by uNK cells. The protocol my fs uses (prednisolone pre-preg) makes it difficult to fall pg so after 12 months ttc on pred with 3 cycles of Clomid we did ivf. I also have 2 friends with genetic disorders who had to do pgd in order to have healthy babies but had no conception issues. So I agree with pp's that there are many reasons for requiring ivf that may not be fully disclosed in a news article.
I started ivf at 31 after ttc since I was 26 so 5yrs. I had 3 mc's AND my mum started menopause at 36, I also have low ovarian reserves so age shouldn't be a discriminatory factor for ivf.

Edited by DragonsGrace, 20 February 2013 - 02:25 PM.


#12 jules095

Posted 20 February 2013 - 03:26 PM

QUOTE (eyesabove @ 20/02/2013, 01:48 PM) <{POST_SNAPBACK}>
I agree. It absolutely depends on what the reasons for infertility were. The PP has no way of knowing that either. I find blanket statements about those of us in our 20's 'rushing' into IVF unhelpful - sometimes there are genuine reasons.
FWIW, if you are taking about DC making a blanket statement, she was in her early 20's when she first started IVF, so without her sig, you have no way of knowing HER journey, or knowledge of AC either.


QUOTE (eyesabove @ 20/02/2013, 01:48 PM) <{POST_SNAPBACK}>
This woman's treatment could have involved months and levels of AC that are undisclosed in the article prior to the patient undertaking the IVF attempt. It doesn't even specify that the successful attempt was her first IVF cycle either.
Why not state the truth then, rather than just producing the success rate. Say she did other AC treatments & not just say she TTC'd for 6mths & then fell pg after this fantastic, IVF breakthrough.


#13 LittleListen

Posted 20 February 2013 - 04:14 PM

QUOTE (jules095 @ 20/02/2013, 04:26 PM) <{POST_SNAPBACK}>
FWIW, if you are taking about DC making a blanket statement, she was in her early 20's when she first started IVF, so without her sig, you have no way of knowing HER journey, or knowledge of AC either.


Why not state the truth then, rather than just producing the success rate. Say she did other AC treatments & not just say she TTC'd for 6mths & then fell pg after this fantastic, IVF breakthrough.


You are right, I have no way of knowing DC's journey from this thread alone - and I made no statement about DC's journey or anyone else here. I do find blanket statements against the use of IVF for younger women frustrating.

The article was specifically related to the addition of the gel to the process. Regardless of the young women's previous cycle history, the gel is being touted as the defining characteristic this case.

The study results are in early stages and this report focuses on what data has already been released from the company. Given that they now only use this gel as in my previous link, they obviously feel strongly positive about its use in improving outcomes.

Surely with such a diverse conception-method and infertility community on this forum, we can find a way to discuss these topics without the need for general statements related to IVF and age (and yes, I'm aware that this forum is regularly awash with judgement calls for the 'Upper age Limit" for women undergoing IVF - something I also I have a problem with).

I was merely suggesting that panning the results of s study of over 600 women because one of them had six months TTC and was in her 20's is near-sighted.

As a patient of the clinic in question, I am also aware that the clinic refers to AC cycles in some cases as 'natural' cycles even though they involve the use of drugs, to differentiate between those and the women who are undergoing IVF procedures. This may also add to the confusion.



1 user(s) are reading this topic

0 members, 1 guests, 0 anonymous users

 

Special offer: The Baby & Toddler Show 2014

At The Baby & Toddler Show, you?ll find everything you need to get ready for your new arrival and guide you through the early weeks and years of parenting.

The words I hated hearing as new mum

It was less than a week after my son was born that I first heard it - from my mother.

To the pharmacist who sold me baby formula

On the rare occasion I catch sight of you at school, or around town, I think back to our earliest exchange. I?m sure you have no recollection of it at all.

Babies may benefit from autism therapy

Children showing signs of autism don't usually receive early intervention until well into toddlerhood or later, but a new study suggests infants with symptoms of the developmental disorder might benefit from therapy from as early as six months.

Knatalye and Adeline born with an everlasting bond

Knatalye Hope and Adeline Faith are a lot like any other identical twin girls, but there is one dramatic difference: they're joined at the chest and shares several internal organs.

The question this dad wishes he'd asked his wife

I should have seen that my wife wasn't the same person I'd fallen in love with, but we were both too focused on simply trying to get by.

Why we should talk about the deaths of the Hunt children

The deaths are too horrible even to think about. Yet we owe it to the children - Fletcher, Mia and Phoebe Hunt - to think long and hard about it all.

Baby dies of meningococcal weeks after vaccine application denied

A six-month-old girl has died from meningococcal disease just weeks after an application for government funding of a vaccine for the most deadly strain of the virus was rejected.

Finding the right balance when playing with your kids

Being too involved in our children?s play and not allowing our kids enough free time for unstructured activities can mean our kids miss out on the value that play offers.

Creative DIY light shades

The Pop Light light shade comes in a flat pack already made - it's up to you to design it as you'd like.

The battle of iParenting versus imagination

Have we forgotten how to be imaginative, resourceful parents?

Why movement is so important for your baby's growth

Letting your child move as much as possible in the early years ? using all senses, engaging in the real world, preferably outside ? will help them grow up healthier, smarter, calmer and stronger.

Video: Toddler not keen on clean-shaven dad

This little girl thought she was taking part in a standard game of peek-a-boo, but her dad had a surprise for her.

When will I feel like myself again?

At some point I became 'me' again, but not the same me that I was ... and that?s not a bad thing.

Our Watch: ending the national emergency of domestic violence

An ambitious new national initiative aims to address the "national emergency" of domestic violence across Australia.

Decrease in stillbirths in late pregnancy and older mums

There has been a fall in the number of stillbirths among some groups of women despite the overall rate remaining stable, a new report reveals.

My baby was permanently injured during birth

My baby was a few months old when we first heard the term ?brachial plexus birth injury? and the heart wrenching news that he may never gain full function of his arm.

Being a yo-yo mama is the rhythm of motherhood

A flip-flop happy-sad can occur in the same minute, the same second. And it continues forever, throughout a yo-yo mama's tenure, beginning with pregnancy.

Is it okay to ask for money instead of gifts?

First it was weddings. Then it was engagement parties. Now it seems christenings are following the trend of asking guests for money in lieu of gifts.

Crash testing new parenthood

The new documentary series Crash Test Mummies & Daddies takes a fly-on-the-wall look at the first months of life with a newborn.

Itching for a solution to eczema

Around 30 per cent of children live with eczema every day. A dad shares his son's story and gets advice from an expert.

Video: The challenges and joys of making new mum friends

This hilarious video shows how making new mum friends can be awkward - but reassures that it is possible.

Download now: Essential Kids Activity Finder app

Got bored kids? Quickly find the best activities for kids wherever you are in Australia with the Essential Kids app.

 
Advertisement
 
Advertisement
 
 
 

What's hot on EB

Special offer: The Baby & Toddler Show 2014

At The Baby & Toddler Show, you?ll find everything you need to get ready for your new arrival and guide you through the early weeks and years of parenting.

Win a House of Magic prize pack

To celebrate the release of the new movie House of Magic, we have 10 double passes and magic sets to give away just in time for these school holidays. Enter Now for a chance to win!

Win a Dress Up Attack Family Pass

Sydney's music festival for kids and grown ups this weekend, and we have a family pass to giveaway. Enter Now - entries close Thursday 11th September!

Win back some precious time and get FREE coupons

Membership to eBay's Bubs? Corner is free and includes a $10 coupon to spend on nappies each month - a win for multitasking mums!

Losing yourself to motherhood

While watching your baby grow into a unique little person is exciting and wondrous, the intensity of meeting everyone else?s needs can ever so sneakily overtake your own needs for self-care.

Tearing during delivery: the facts

Almost all women will experience bruising, grazing or tearing after a vaginal birth. Depending on the degree of tearing, there are various treatments available.

6 tips for a day out with a baby and toddler

Outings can be lots of fun with the kids, but there are inevitable challenges. Here's some information about days out to help you be a little more prepared.

Why I invited a dozen people to watch my son's birth

I sent invitations on burgundy scrapbooking paper stamped with a field of poppies, and told each person why I wanted him or her there. I warned that there would be nudity.

Getting labour started: tips for a natural induction

When your baby?s due date comes and goes without so much as a pop - let alone a bang - it can be disheartening. Mums and a doula share their stories of natural inductions.

7 mistakes old hands make with new babies

As I sat across the table from my friend ? me, a seasoned mother of three; her, a brand new mum ? I thought of all the mistakes an old-hand parent can make when visiting a newborn baby.

That's my boy: a dad's diary of the first 4 months

Unbearable anxiety, unspeakable joy, constant exhaustion and bouts of frustration ... The many shocks of first-time fatherhood resound in a dad's diary of his son's early months.

One of the most important things a new mum can do

Finances may not be as cute as a newborn, but with many women?s working arrangements changing post-baby, monetary matters need attention too.

Mum blasted for breastfeeding on train

Breastfeeding may be legal everywhere in Australia - yes, even on public transport - but that doesn't stop the complaints, as a mum learnt.

Personalised baby gifts

We've scoured the internet to find gorgeous personalised keepsakes and nursery decor to record baby name and dates. They make great gifts for christenings, name days and birthdays! (All prices in AU.)

 

Reader offer

2 FOR 1 TICKET OFFER

For Shopping, For Advice, For Baby & You. Enjoy a special day out with fabulous shopping from over 200 brands, leading parenting experts offering advice on a range of topics, and amazing children?s entertainment

 
Advertisement
 
 
Essential Baby and Essential Kids is the place to find parenting information and parenting support relating to conception, pregnancy, birth, babies, toddlers, kids, maternity, family budgeting, family travel, nutrition and wellbeing, family entertainment, kids entertainment, tips for the family home, child-friendly recipes and parenting. Try our pregnancy due date calculator to determine your due date, or our ovulation calculator to predict ovulation and your fertile period. Our pregnancy week by week guide shows your baby's stages of development. Access our very active mum's discussion groups in the Essential Baby forums or the Essential Kids forums to talk to mums about conception, pregnancy, birth, babies, toddlers, kids and parenting lifestyle. Essential Baby also offers a baby names database of more than 22,000 baby names, popular baby names, boys' names, girls' names and baby names advice in our baby names forum. Essential Kids features a range of free printable worksheets for kids from preschool years through to primary school years. For the latest baby clothes, maternity clothes, maternity accessories, toddler products, kids toys and kids clothing, breastfeeding and other parenting resources, check out Essential Baby and Essential Kids.