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TTC after Ectopic surgery and Methotrexate


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#1 munas8

Posted 24 January 2013 - 10:44 AM

Hi All, I have a 3 year old and have been TTC for 2 years/ I had some tests after one year and had some surgery to remove fibroids, I was then put on Clomid to help me ovulate. In june last year I fell pregnant and MC at 6 weeks, In November I then fell pregnant again but it was ectopic and I had to have surgery both tubes remained. A few weeks after this through doing many blood tests they found that the ectopic was not fully removed so I had a methotrexate injection on Dec 24th. as at today my level are back to 0 and the hospital drs told me I can start taking my folate my need to wait 3 months before TTC my private dr however has told me to wait 6 months!!  Has anyone had any simlar stories? I am really struggling after this ectopic.. I think I am emotionally exhausted and just sad. Any shed some success stories of TTC after having something similar?

Thanks in advance to those that reply I have read lots of forums but have never really shared my story before.

Edited by munas8, 24 January 2013 - 10:45 AM.


#2 Nelly77

Posted 24 January 2013 - 01:14 PM

Hello, this is my first time adding a comment on here too. I also had an ectopic last year with two methotrexate injections (no lose of tubes). I was advised that once my hcg levels were at zero, then to wait 3 months before trying.
i would have thought as i needed 2 injections, the wait time would have doubled to 6months but my ob said that 3 months was fine.
sorry to hear of your loss. this is my second loss, so im hoping 3rd time lucky for baby #1!
maybe a second opinion just for re-assurance? Thats what i think i would do. Good luck xx

#3 elizabethany

Posted 24 January 2013 - 01:25 PM

I haven't had methotrexate for an ectopic, but I was taking it weekly for arthritis.  After having a chat to my specialist, she said that I needed at least 3 months after the methotrexate to clear the system before TTC.  I was on a lower dose, but much more frequent (weekly dose for 3 years). 6 months is an old recommendation, but it also makes doubly sure it is all gone.

Unfortunately, methotrexate is really nasty stuff, it is a chemotherapy drug, and can cause birth defects and miscarriage if there is any in your system while pregnant.  Also, ask your doctor for something like Megafol, as methotrexate can interfere with the uptake of folate, so you will need a larger dose.  I take 10mg weekly on top of my TTC/pregnancy vitamins.

Edited by elizabethany, 24 January 2013 - 01:26 PM.


#4 Nelly77

Posted 24 January 2013 - 01:39 PM

I also take Megafol now (higher dose folate)as suggested by my ob with preg vitamins, due to my last two experiences. As elizabethany suggested,we will need to wait at least 3 months due to the seriousness of Methotrexate.

#5 munas8

Posted 24 January 2013 - 04:42 PM

Thanks everyone - I am definently going to wait 3 months as I dont think  im emotionally ready to fall pregnant any sooner. It also usually takes me 3 months or so to actually conceive. To be honest Im a little scared and worried that the methtrexate will affect my baby.

#6 Nelly77

Posted 24 January 2013 - 04:46 PM

Exactly, its just not worth risking! Our first loss, our baby had many abnormalities (no relation to our second loss being ectopic) and really dont want to experience that again. Best to wait and give our bodies a rest at the same time i think. Wishing you all the best.

#7 Corella

Posted 24 January 2013 - 04:47 PM

It also depletes your B12 levels so get that checked too.

#8 Minxybug

Posted 25 January 2013 - 05:24 AM

With my ectopic I lost the right tube as it had ruptured. I was told then if I had the methotrexade (sp?) then I would need to wait 3 months as it takes at least 12 weeks to leave to system.

I always wait a month after being 'in the clear/ready TTC' before trying again  

I hope that your next pregnancy is strong and healthy and that it ends with a precious baby in your arms.

#9 *Katey*

Posted 25 January 2013 - 09:12 AM

Hi original.gif

I had surgery for my ectopic in Dec 2011. I had to have my tube removed as it had ruptured, and didn't need the injection. My OB advised me to wait only 4 - 6 weeks until I had healed from surgery before TTC again, but that's because I didn't have the injection. I read though, in my research following my ectopic, that if you had the injection, it's recommended to wait 3 months until it fully leaves your system.

In regards to success stories, I am now almost 31 weeks pregnant with our little boy original.gif

Fingers crossed you'll have a success story of your own soon as well original.gif

Edited by *Katey*, 25 January 2013 - 09:13 AM.


#10 munas8

Posted 25 January 2013 - 07:38 PM

Katey glad to hear your success story. I'm hoping I will have one also, I def will start trying as soon as 3 months is up. It's a waiting game. I am hoping 2013 is a lucky year for us I'm not sure I could go through another loss.

Thanks for support everyone it's nice to have people to share this with.

Edited by munas8, 25 January 2013 - 07:39 PM.


#11 elizabethany

Posted 25 January 2013 - 07:49 PM

I automatically turn of my sig in TTC, but I just saw that you wanted to hear about success stories.  Iam 16 weeks pregnant, after 3 years of methotrexate, and had my DS after taking it too.  Apart from delaying TTC until 3 months from final dose, it does not interfere with TTC or pregnancy if you follow the exclusion time.

#12 munas8

Posted 26 January 2013 - 10:40 PM

Thanks Elizabethany it's great to hear your story and gives me hope. Congrats on the 16 weeks


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