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Cat freaking out, any ideas?

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#1 BadCat

Posted 05 December 2012 - 08:44 PM

My cat is old.  Really, really old.  She has arthritis.  This morning the vet prescribed Tramadol and gave her her first capsule.  Since she had it at about 10.30 this morning she has not slept, has barely stayed in one place for more than five minutes.  Her pupils are quite dilated and she stares at stuff in a weird way.  Basically she's tripping.  Still.  Eleven hours later.  Needless to say we have not given her her second dose.

I put in a call to the vet but she didn't manage to get back to me today.  I'm concerned that my cat hasn't "come down" yet.  Should I be worried?  Is there anything I can do except wait for it to clear her system?

I hate seeing her freaking out like this.  sad.gif

#2 TopsyTurvy

Posted 05 December 2012 - 08:52 PM

Poor thing sad.gif

Is there a 24hour vet clinic near you. Might be worth giving them a call to see what they say.  If there is nothing they can do to counteract it, then you most possibly will have to just wait it out.

I guess lots of love and pats are needed original.gif

#3 kadoodle

Posted 05 December 2012 - 08:55 PM

Oh the poor thing  sad.gif

Darkened room maybe?

#4 Marchioness Flea

Posted 05 December 2012 - 08:57 PM

I think you can use rescue remedy on pets, but if you don't have any, I doubt you'd be able to get some this time of night.

#5 pundelina

Posted 05 December 2012 - 09:02 PM

Don't give cats alcohol. Rescue remedy is alcohol based.

Dark room & quiet time OP.

#6 Madnesscraves

Posted 05 December 2012 - 09:02 PM

Are you in NSW? There's a emergency vet hospital in Ryde?

Personally that would concern me greatly. She must have had a bad reaction to the meds. sad.gif poor thing. Have you tried feeding her so its absorbed by food and out of her system sooner?

ETA: please don't feed her donuts. Autocorrect does not know better...

Edited by Madnesscraves, 05 December 2012 - 09:04 PM.

#7 Paddlepop

Posted 05 December 2012 - 09:03 PM

Perhaps the dosage was too high for her. When my dog was getting quite old she needed only about half the dose of Xanax that she was supposed to have according to her weight.

Does she have any liver problems? This article mentions that if the liver function is impaired then it could lead to an overdose because the cat's body can't clear the drug at the correct rate.

You probably just need to wait it out and then review the dosage with the vet and probably get a lower dose prescribed and try her with that. Otherwise, try a 24 hour vet if there are any nearby.

Poor cat. Give her some extra cuddles if she will accept them. It must be very confusing for her.

#8 purplekitty

Posted 05 December 2012 - 09:06 PM

Not a vet but I just looked it up and it seems Tramadol is cleared by the liver and kidneys in cats,similar to humans.
An elderly cat may have reduced function in both of these areas causing prolonged high levels and a longer duration of action.
Tramadol is a weak opiate so has some of the side effects of opiates.

I think it's worth seeking the advice of a 24hr. vet if you can.

Rescue Remedy will do nothing.

ETA; I hope there are some vets around on EB tonight and everything settles down for your puss.

Edited by purplekitty, 05 December 2012 - 09:09 PM.

#9 BadCat

Posted 05 December 2012 - 09:13 PM

She's in a dark room.  She has been eating, in fact she seems ravenous.  She has finally agreed to sit on a cushion on DH's lap but she will not close her eyes.  sad.gif

Her liver function is OK but her kidney function is not so good.  The vet knows that though and should have taken it into account.

Might see if they have an after hours number.  Thanks for the suggestions guys.

And no MadnessCraves, donuts were not on the menu.  laughing2.gif

#10 squirt081

Posted 05 December 2012 - 09:17 PM

QUOTE (pundelina @ 05/12/2012, 10:02 PM) <{POST_SNAPBACK}>
Don't give cats alcohol. Rescue remedy is alcohol based.

Yes you can give Rescue Remedy, The All Natural Vets in Balmain NSW recommends it for stressed animals.

Edited by squirt081, 05 December 2012 - 09:17 PM.

#11 BadCat

Posted 05 December 2012 - 09:19 PM

I don't have any Rescue Remedy anyway but would be reluctant to give it anyway given that I don't know what the Tramadol is doing to her system.

#12 pundelina

Posted 05 December 2012 - 09:23 PM

QUOTE (squirt081 @ 05/12/2012, 10:17 PM) <{POST_SNAPBACK}>
Yes you can give Rescue Remedy, The All Natural Vets in Balmain NSW recommends it for stressed animals.

Just because a woo vet recommends giving alcohol to a cat doesn't mean that the OP should give her whacked out cat more mind-altering substances.

Bach's Flower Remedies are woo medicine at the peak of woo-iness.


editing for spelling original.gif

Edited by pundelina, 05 December 2012 - 09:46 PM.

#13 purplekitty

Posted 05 December 2012 - 09:30 PM

QUOTE (pundelina @ 05/12/2012, 09:23 PM) <{POST_SNAPBACK}>
Bach's Flower Remedy's are woo medicine at the peak of woo-iness.
Quoted for truth.

#14 squirt081

Posted 05 December 2012 - 09:32 PM

Thats your opinion, I have seen it work and I dont normally think that these sort of things work.

#15 ~ppp~

Posted 05 December 2012 - 09:47 PM

Dilated pupils, dysphoria, excitement etc are adverse reactions seen occasionally in cats with tram afoul (randomly occurs in occasional cats, nothing your vet could predict or influence). In low doses its usually a good choice for old cats with dodgy kidneys. Generally it passes in 24hrs but obviously get your cat checked and speak with the vet who prescribed it to see if anything further needs to be done in your particular case.

#16 Feral*Spikey*

Posted 06 December 2012 - 06:10 AM

RR works on humans because of the placebo effect (and the alcohol).

As animals are not able to assume they are getting 'real' medicine, there is no placebo effect in the animal kingdom.

Consequently, RR doesn't have a clinical effect on an animal. However, further studies have shown that owners who give RR to their pets perceive a difference (the placebo effect again), despite the difference being simply the normal rate of recovery.

In otherwords, it doesn't work, except on the humans, when given to animals.

Back to vet for your poor kitty.

#17 TopsyTurvy

Posted 06 December 2012 - 06:25 AM

How is your cat today BC?

I hope everything settled down and you managed to all get some sleep.

#18 BadCat

Posted 06 December 2012 - 06:30 AM

I did manage to get hold a vet last night who asked a few questions about the state she was in and said as long as she doesn't get worse that we should just ride it out.

She is quite a bit better this morning.  Still not quite back to normal but resting and perhaps even sleeping a bit.

I'll contact my own vet this morning for some different meds.

Thank you all for your suggestions.

#19 Unatheowl

Posted 06 December 2012 - 06:36 AM

Glad to hear it.  This reaction is not unheard of particularly in cats.  It's a shame as it is a really great drug for so many reasons.  I'm sure your vet will find one that works well for her.

#20 runnybabbit

Posted 06 December 2012 - 11:00 AM

Another vet late to the party, sorry OP. Glad to hear your cat is doing better today. Unfortunately when trying new medications it can be a matter of trial and error. Some dogs trip out on tramadol as well. (My MIL does, too, apparently -- found this out when she was given tramadol post knee replacement.)

Hopefully a good dose and/or combination of drugs will be found for your cat. It might take a bit or a lot of tweaking here and there.

Generally when I have a patient have a dysphoric reaction to opioids or related drugs, minimising stimuli is what I do -- darkened room, no sudden noises or movement, etc, in a padded cage so they can't hurt themselves. Depending on the drug and the severity of the reaction you can give naloxone to reverse some of the opioid binding, but this would involve a trip to the vet and likely admission as the half-life of naloxone isn't very long.

Good luck OP!

#21 BadCat

Posted 06 December 2012 - 12:31 PM

Thanks Runnybabbit and UnatheOwk.  She's much better now and is back in her standard postion of snoozing on the deck in the sun.

Will follow up with the vet and find something more suitable for her.

#22 purplekitty

Posted 06 December 2012 - 12:48 PM

I'm glad your cat is doing better,Badcat.
QUOTE (runnybabbit @ 06/12/2012, 11:00 AM) <{POST_SNAPBACK}>
Some dogs trip out on tramadol as well. (My MIL does, too, apparently -- found this out when she was given tramadol post knee replacement.)
I had to smile when a PP autocorrected Tramadol to Tram afoul.Somewhat appropriate.
It obviously has the same problems in animals as humans,my elderly Mum included.

#23 Therese

Posted 07 December 2012 - 08:45 PM

I'm so glad she's ok now original.gif

#24 Unatheowl

Posted 07 December 2012 - 08:55 PM

QUOTE (purplekitty @ 06/12/2012, 01:48 PM) <{POST_SNAPBACK}>
I'm glad your cat is doing better,Badcat.
I had to smile when a PP autocorrected Tramadol to Tram afoul.Somewhat appropriate.
It obviously has the same problems in animals as humans,my elderly Mum included.

Yes, friend of mine has had it and started vomiting within 1 hour with dyspohoria.  I had taken it myself for broken bone and found it very effective with no side effects.  I have also prescribed it to arthritic animals, particularly cats, with great results.  It just depends upon the person/animal....

#25 kadoodle

Posted 07 December 2012 - 09:00 PM

I had it when I broke my coccyx and no drama.  My youngest sister was given some when she broke her ankle and she went vicious, it was like she was on cocaine.

How is she today, OP?

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