Jump to content

Empty follicles on 3 different egg collections
Please help

  • Please log in to reply
9 replies to this topic

#1 destiny31

Posted 21 November 2012 - 02:01 PM

Hi everyone,
I am a new member and this being my first post. However my husband and I have been trying to conceive for about 3 years now.
I have had 4 ivf attempts. I am a poor responder.
my first ivf attempt was cancelled due to only a few follicles.
my second attempt i only had 7 follicles , when when i went into egg collection they said all follicles were empty. we were devastated.
my third attempt was the same, went in for egg collection - follicles again were all empty.
my fourth attempt and 3rd egg collection - the same, this time i had about 10 follicles but ALL EMPTY once again.
This time the doctor had changed the protocol, put me on a different trigger, i took the synarel nasal spray instead of the ovidrial, but it didnt help.

Has anybody ever experienced empty follicles, especially more than once? I guess im a really rare case, not even my doctor knows what to do next.

Any advise/help is appreciated.

Edited by destiny31, 21 November 2012 - 02:15 PM.

#2 kez71

Posted 21 November 2012 - 02:34 PM

I'm so sorry. You must be devastated. From my own reading in various IVF forums and blogs it appears that empty follicles are not truely empty, just the eggs are not mature enough to release. This can be changed by varying protocols and triggering with different drugs and timings.
My advice to you would be to google Empty Follicle and see if anything rings true for you. You may need to change doctor, especially if he feels at a loss what to try next. Don't give up yet! Good luck

#3 babycuddler

Posted 21 November 2012 - 02:54 PM

Oh you poor thing! I really hope your specialist can change your medication and you can get some eggs happening! They should also be able to recommend some supplements for you to take and give you a rest before trying again! Also I recommend thinking about a 'plan B' even though it is early days. In my case (I'm not a great responder) my sister has offered her eggs, but it takes time for me and particularly my husband to get his head around the idea. There will be some ladies on here with some great advice I'm sure! Good luck with it all

#4 Schoolmum12

Posted 21 November 2012 - 03:03 PM

I'm pretty sure I read a post about this years ago.  I'll see if I can find it for you.

I'm pretty sure Derek Lok from Genea (then Sydney IVF) has written a paper about it.

From memory, a lucrin trigger was required.

I'll keep hunting.

Good luck.

Edited by ivfmiracles, 21 November 2012 - 04:17 PM.

#5 Schoolmum12

Posted 21 November 2012 - 04:18 PM

Found It!!!


QUOTE (embracingIVF @ 08/04/2009, 12:23 PM) <{POST_SNAPBACK}>
Hi ladies

I happen to be a bit of an expert in this area. I have had a similiar situation and was lucky enough to change doctor's - my third cycle I saw Dr Lok at SIVF. He has wriiten a research paper on this topic. It has to do with your own LH surge being immune to the trigger shots. If you are lucky it can just be changing the trigger to pregnyl and upping the dose.

From Dr Lok's research he found its best to do an antagonist cycle and then use lucrin to trigger your own LH surge. Which for me worked  ddance.gif cannot even explain how much of a releif it was to find Dr Lok who said it has nothing to do with my ovarian reserve or fertility it is just a reaction to the trigger shot.

PM me if you need more info but I would highly recommend contacting Dr Lok at SIVF, my previous cycles were with Dr Bowman (who is the director of SIVF and he had NO idea what was happening - so I think most doctors are not familiar with this problem)....

good luck tthumbs.gif

#6 domestically~challenged

Posted 22 November 2012 - 11:57 AM

Although empty follice syndrome is rare it must be hard when it keeps happening and you clinic doesn't know what to do next after already changing protocol sad.gif

If it were me I would look at changing clinics for a second opinion before looking into donor eggs.

Good luck with everything hhugs.gif

#7 babycuddler

Posted 22 November 2012 - 12:50 PM

Well done ivfmiracles!!

#8 Handsfull

Posted 22 November 2012 - 12:54 PM

Awesome post ivfmiracles.  Very interesting reading.  

Things have so changed since I did my IVF.

Edited by handsfull, 22 November 2012 - 12:54 PM.

#9 embracingIVF

Posted 22 November 2012 - 01:25 PM

hi destiny

i am the one who went with dr lok for baby number 1 and had had two ivf attempts where all eggs were immature. PM me for more info as i then had the same problem again when we went for baby number 2. so i am a bit of an old hand at this very stressful problem.


#10 destiny31

Posted 22 November 2012 - 08:00 PM

thanks everyone for your replies and comments.
hearing the news from the doctor again saying all empty, no eggs is the worst news ever. unfortunately ive experienced it 3 times, what is more frustrating is that the doctors have no answers, no idea, no direction. it has happened with 2 different doctors now. i will keep researching and hopefully one day have a successful cycle.

1 user(s) are reading this topic

0 members, 1 guests, 0 anonymous users


Newborn baby found in a nativity scene

Police are trying to trace a woman who abandoned a baby boy in the manger of a church nativity scene.

Life would be harder without my kids

The Humans of New York Facebook page is well known for sharing touching, real stories from one of the world's biggest cities – and it's just hit the heart of parents everywhere.

Mum dresses as Wonder Woman for last day of chemo

A Brisbane mum dressed up as a superhero to celebrate the end of her chemotherapy and created a moment her family will remember forever.

How a raisin can predict a toddler's IQ

All you need to assess a child's future intelligence is a plastic cup and a raisin, according to new research.

Former Hi-5 member's cannabis hope

Former Hi-5 star Tim Harding hopes a cannabis-derived drug will help control his daughter's epilepsy, which sees the four-year-old suffering between 50 and 100 seizures a day.

The top 5 reasons your toddler throws a tantrum

Whilst to the outside world little people may appear to have it easy, it's actually not always the case – just ask any toddler who's had their toast cut up the wrong way.

Glenn McGrath thought he'd lost his wife and baby

Australian cricket ledged Glen McGrath has spoken about the moment he thought he might lose his wife, Sara and their baby daughter, Madison.


Inside my Centrelink nightmare

Mother Bec Smith has been trying for months to access Centrelink payments. A "serious error" is preventing her.

Warnings over push for hourly childcare billing

Australia's peak childcare body has called for caution around the Turnbull government's push for childcare centres to charge parents by the hour, not by the day.

Cate Blanchett thought about adopting for years

Cate Blanchett says her recent adoption of a baby girl had nothing to do with wanting a daughter after having three sons.

Kate Walsh: 'I can't have kids'

Grey's Anatomy star Kate Walsh has revealed she is unable to have children because she has experienced early menopause.

The parasite that could boost fertility

The Tsimane women of Bolivia are often revered as among the most fertile in the world - on average having 10 children in their lifetimes -- but some are even more fertile than others.

Family may sue cousin over genetics

A Melbourne couple is suing the Royal Children's Hospital for failing to diagnose a genetic disorder in their first child - an error they allege caused them to have another child with severe disabilities.

Strange things mums have done in labour

While most women in labour focus on the upcoming birth of their baby, some women do more interesting things.

Michael Clarke reveals baby's name

When Michael Clarke said he was wrapped around the finger of his little princess, he wasn't joking.

The logistics of breastfeeding twins

Our life is more or less divided into neat four hour parcels of time and it's hard to get much of anything done in the time between feeds.

How to stop people ruining Christmas

We can make a conscious effort about how we react to those curly Christmas day scenarios that can send us up the wall, or should we say chimney.

Lots of formula offers for desperate mum

The mum who was down to her last three tins of baby formula said she had received hundreds of calls and offers to send her formula.

Surviving breast cancer while pregnant

It was last thing Rebecca O'Donnell expected at 30 weeks' pregnant. One morning, while putting on her bra, she felt a pea-sized lump in her right breast.

Cot sheet brands for the nursery

With so many awesome cot sheet options these days, we thought we'd put together a list of go-to brands for you to seek out for your baby's bed.


What's hot on EB

How I survived breast cancer while pregnant

It was last thing Rebecca O'Donnell expected at 30 weeks' pregnant. One morning, while putting on her bra, she felt a pea-sized lump in her right breast.

Grieving father's letter to Bataclan terrorists: "...this little boy will threaten you by being happy and free"

A grieving father whose wife was killed in the attacks on the Bataclan Theatre last weekend has written an open letter to her killers.

5 challenges of motherhood - and how to see them differently

Despite the smiles, the sloppy kisses and the pure magic children bring to our lives, it's hard to deny that motherhood can be tough.

4 challenges of being a new dad - and how to face them

Becoming a parent is challenging – and that applies to both mums and dads.

My battle against antenatal and postnatal depression

I was five months pregnant when I realised I needed help.

Children swapped at birth will not be returned to biological parents

A boy and girl accidentally swapped on the day they were born will stay with the families who have raised them, a South African court has ruled.

A quarter of men believe they get 'man periods'

A British study has revealed one in four men believe they have a monthly cycle.

Baby deposit

How much do you need to save for a 'baby deposit'?

It's fairly straightforward to calculate a house deposit, but how much money do you need to save up for a baby?

Dad's beautiful note to his wife, a nurse

To anyone else it might just look like a picture of a mum having a nap with her toddler.

'I was a complete schmuck': Mike Baird opens up about his wife's postnatal depression

When his wife Kerryn was not well following the birth of their daughter, NSW Premier Mike Baird buried himself in his work.

Mum's desperate plea as whooping cough alert issued

A desperate mother has shared a heart-breaking video of her baby struggling to cope with a coughing fit caused by pertussis.

Coffee could help you live longer

New US research found people who report drinking three to five cups of coffee a day are less likely to die prematurely from heart disease, suicide, diabetes or Parkinson's disease.

The joy and dread of playdates

To live vicariously through your child is to rediscover anxieties you thought dead and buried.

Sick baby could die without scarce special formula, mum says

Lizzie Cann is down to her last three tins of a special formula in short supply.

Adorable toddler's strop foiled by squeaky shoes

We're probably all familiar with the pouty bottom lip and tightly crossed arms of a tot mid-strop.

More sex during World Cup created more baby boys

More sex during South Africa's World Cup meant a disproportionately high number of boys were born nine months later, a new study has found.

Win one of two ABC Shop prize packs in time for Christmas

What a boon it would be to have your toddler's Christmas gifts covered this year. We have two awesome ABC Shop prize packs to give away to two lucky winners.

Do fitness challenges really work?

Fitness challenges aren't new. There's Michelle Bridges 12WBT and a bunch of other programs if you really want to lose weight.

What are pregnant women Googling?

Pregnancy is a huge change for any woman, so it's natural we'll have questions - and turn to Google to ask them.



Can't decide?

Check out the Essential Baby Names section for some inspiration

Essential Baby and Essential Kids is the place to find parenting information and parenting support relating to conception, pregnancy, birth, babies, toddlers, kids, maternity, family budgeting, family travel, nutrition and wellbeing, family entertainment, kids entertainment, tips for the family home, child-friendly recipes and parenting. Try our pregnancy due date calculator to determine your due date, or our ovulation calculator to predict ovulation and your fertile period. Our pregnancy week by week guide shows your baby's stages of development. Access our very active mum's discussion groups in the Essential Baby forums or the Essential Kids forums to talk to mums about conception, pregnancy, birth, babies, toddlers, kids and parenting lifestyle. Essential Baby also offers a baby names database of more than 22,000 baby names, popular baby names, boys' names, girls' names and baby names advice in our baby names forum. Essential Kids features a range of free printable worksheets for kids from preschool years through to primary school years. For the latest baby clothes, maternity clothes, maternity accessories, toddler products, kids toys and kids clothing, breastfeeding and other parenting resources, check out Essential Baby and Essential Kids.